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PMID: 16912951 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Acute respiratory distress syndrome and pneumonia: a comprehensive review of clinical data.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America ·Vol. 43 ·No. 6 ·2006-09-15 ·Pages 748-56

Bauer TT, Ewig S, Rodloff AC, Müller EE

Abstract

Acute respiratory distress syndrome (ARDS) and pneumonia are closely correlated in the critically ill patient. Whereas ARDS is often complicated by nosocomial pneumonia, pulmonary infection is also the most frequent single cause of ARDS. The prevalence of pneumonia during the course of ARDS seems to be particularly high, but whether persons with ARDS are more susceptible to pneumonia or simply have more risk factors remains unknown because of methodological limitations. Recent research suggests that host factors have a major bearing on the development of ARDS. To date, sepsis seems to be the principal link between pneumonia and ARDS. However, prospective observational data on this supposed sequence are not available. The individual role of specific pathogens for the development of ARDS is difficult to assess, because prospective studies are missing. Respiratory viruses have received particular attention, but this review suggests that infections with coronavirus and avian influenza virus (H5N1) are associated with a high incidence of ARDS.

MeSH Terms
Animals Bacteria/isolation & purification,pathogenicity Coronavirus/isolation & purification Disease Susceptibility Humans Influenza A Virus, H5N1 Subtype/isolation & purification Parasites/isolation & purification,pathogenicity Pneumonia/complications,epidemiology,microbiology Respiratory Distress Syndrome/complications,epidemiology,microbiology Respiratory Tract Infections/complications,epidemiology,virology Risk Factors Sepsis/complications
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Bauer Torsten T
Helios Clinic Emil von Behring, Respiratory Diseases Clinic Heckeshorn, Berlin, Germany. [email protected]
Ewig Santiago
Rodloff Arne C
Müller Eckhard E
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Article Info
Journal
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Abbr.
Clin Infect Dis
ISSN
1537-6591
DOI
10.1086/506430
Email
[email protected]
Published
2006-09-15
Epub
2006-00-10
Pages
748-56
Language
English
Region
United States
NLM ID
9203213
PMCID
PMC7107989
Subset
IM
External Links
PubMed source DOI: 10.1086/506430 PMC Full Text View journal details
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