Home LiteratureArticle Details
PMID: 16959565 Published · ppublish English Journal Article Review

Chemical technologies for probing glycans.

Cell ·Vol. 126 ·No. 5 ·2006-09-08 ·Pages 851-4

Prescher JA, Bertozzi CR

Abstract

Glycans are central to many biological processes, but efforts to define their functions at the molecular level have been frustrated by a lack of suitable technologies. Here we highlight chemical tools that are beginning to address this need.

MeSH Terms
Carbohydrate Conformation Carbohydrate Sequence Enzyme Inhibitors/pharmacology Glycoproteins/chemistry,metabolism Glycosylation Glycosyltransferases/antagonists & inhibitors,metabolism Green Fluorescent Proteins Molecular Sequence Data Photoaffinity Labels Protein Array Analysis Protein Conformation Protein Processing, Post-Translational/drug effects Proteomics Tunicamycin/pharmacology
Chemicals
Enzyme Inhibitors Glycoproteins Photoaffinity Labels Tunicamycin Green Fluorescent Proteins Glycosyltransferases
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Prescher Jennifer A
Department of Chemistry, Howard Hughes Medical Institute, University of California, Berkeley, CA 94720, USA.
Bertozzi Carolyn R
Article Info
Journal
Cell
Abbr.
Cell
ISSN
0092-8674
DOI
10.1016/j.cell.2006.08.017
Published
2006-09-08
Pages
851-4
Language
English
Region
United States
NLM ID
0413066
Subset
IM
External Links
PubMed source DOI: 10.1016/j.cell.2006.08.017 View journal details
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