Gefitinib concentrations in human glioblastoma tissue.

Journal of neuro-oncology ·Vol. 82 ·No. 2 ·2007-04-00 ·Pages 175-6

Hofer S, Frei K

Abstract

暂无摘要

MeSH Terms

Antineoplastic Agents/pharmacokinetics Biological Availability Brain Neoplasms/drug therapy,metabolism Chromatography, High Pressure Liquid Cytochrome P-450 CYP3A Cytochrome P-450 Enzyme System/metabolism ErbB Receptors/antagonists & inhibitors Gefitinib Glioblastoma/drug therapy,metabolism Humans Quinazolines/pharmacokinetics

Chemicals

Antineoplastic Agents Quinazolines Cytochrome P-450 Enzyme System Cytochrome P-450 CYP3A CYP3A4 protein, human ErbB Receptors Gefitinib

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Hofer Silvia

Medical Oncology, University Hospital Zürich, Rämistrasse 100, 8091, Zürich, Switzerland. [email protected]

Frei Karl

References (2)

2 references, click to expand

Specific method for determination of gefitinib in human plasma, mouse plasma and tissues using high performance liquid chromatography coupled to tandem mass spectrometry.
J Chromatogr B Analyt Technol Biomed Life Sci. 2005 May 5;819(1):73-80 PMID: 15797523
Gefitinib accumulation in glioblastoma tissue.
Cancer Biol Ther. 2006 May;5(5):483-4 PMID: 16582594

Article Info

Journal

Journal of neuro-oncology

Abbr.

J Neurooncol

ISSN

0167-594X

DOI

10.1007/s11060-006-9257-3

[email protected]

Published

2007-04-00

Epub

2006-00-29

Pages

175-6

Language

English

Region

United States

NLM ID

8309335

Subset

External Links

PubMed source DOI: 10.1007/s11060-006-9257-3 View journal details

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Gefitinib concentrations in human glioblastoma tissue.

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