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PMID: 170908 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Esterase-6 (Es-6) in laboratory mice: hormone-influenced expression and linkage relationship to oligosyndactylism (Os), esterase-1 (Es-1), and esterase-2 (Es-2) in chromosome 8.

Biochemical genetics ·Vol. 13 ·No. 5-6 ·1975-06-00 ·Pages 311-22

Womack JE

Abstract

Allelic differences at an esterase locus designated Es-6 exist between mouse strain C57 BL/6J and a laboratory stock of M.m. molossinus. Strain C57BL/6J has been assigned the allele Es-6a and M. m. molossinus the alternate allele Es-6b. Kidney expression of the electrophoretic esterase band controlled by the Es-6 locus is sex influenced, with increased activity apparently induced by testosterone. A four-point test cross established the gene order Os-Es-1-Es-6-Es-2 within a 10-cM segment on chromosome 8.

MeSH Terms

Alleles Animals Castration Chromosome Mapping Esterases/biosynthesis Female Genes Genetic Linkage Kidney/enzymology Male Mice/metabolism Mice, Inbred C57BL Polymorphism, Genetic Sex Syndactyly/genetics Testosterone/metabolism

Chemicals

Testosterone Esterases

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Womack J E

References (16)

16 references, click to expand

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Article Info

Journal

Biochemical genetics

Abbr.

Biochem Genet

ISSN

0006-2928

DOI

10.1007/BF00485816

Published

1975-06-00

Pages

311-22

Language

English

Region

United States

NLM ID

0126611

Subset

External Links

PubMed source DOI: 10.1007/BF00485816 View journal details

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Esterase-6 (Es-6) in laboratory mice: hormone-influenced expression and linkage relationship to oligosyndactylism (Os), esterase-1 (Es-1), and esterase-2 (Es-2) in chromosome 8.

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