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PMID: 171279 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Demonstration of immunoglobulin G receptors induced by human cytomegalovirus.

Journal of clinical microbiology ·Vol. 2 ·No. 4 ·1975-10-00 ·Pages 332-6

Furukawa T, Hornberger E, Sakuma S, Plotkin SA

Abstract

Human cytomegalovirus induced a new immunoglobulin G receptor in human fibroblasts. The immunoglobulin G receptor was well localized in the perinuclear region at 48 h postinfection, and antiviral agents blocked its synthesis. The immunoglobulin G receptor bound immunoglobulin G of man and several other species. It may be a source of error in the performance of indirect fluorescence tests for human cytomegalovirus antibody.

MeSH Terms
Antibodies, Viral/analysis Binding Sites, Antibody Cell Line Cell Nucleus/immunology Child, Preschool Cycloheximide/pharmacology Cytarabine/pharmacology Cytomegalovirus/growth & development,immunology Cytoplasm/immunology Fibroblasts/immunology Fluorescent Antibody Technique Humans Immunoglobulin G Inclusion Bodies, Viral/drug effects Infant Infant, Newborn Virus Replication
Chemicals
Antibodies, Viral Immunoglobulin G Cytarabine Cycloheximide
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Furukawa T
Hornberger E
Sakuma S
Plotkin S A
References (9)
9 references, click to expand
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    J Virol. 1973 Jun;11(6):991-7 PMID: 4351464
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Article Info
Journal
Journal of clinical microbiology
Abbr.
J Clin Microbiol
ISSN
0095-1137
DOI
10.1128/jcm.2.4.332-336.1975
Published
1975-10-00
Pages
332-6
Language
English
Region
United States
NLM ID
7505564
PMCID
PMC362805
Subset
IM
External Links
PubMed source DOI: 10.1128/jcm.2.4.332-336.1975 PMC Full Text View journal details
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