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PMID: 1717852 Published · ppublish English Journal Article

Growing human B lymphocytes in the CD40 system.

Nature ·Vol. 353 ·No. 6345 ·1991-10-17 ·Pages 678-9

Banchereau J, Rousset F

Abstract

One approach to generating human monoclonal antibodies relies on the development of culture techniques allowing the long-term growth of most B lymphocytes, a property of the CD40 system.

MeSH Terms
Antibodies, Monoclonal Antigens, CD/immunology Antigens, Differentiation, B-Lymphocyte/immunology B-Lymphocytes/cytology,immunology CD40 Antigens Cell Division Cell Line, Transformed Herpesvirus 4, Human Humans
Chemicals
Antibodies, Monoclonal Antigens, CD Antigens, Differentiation, B-Lymphocyte CD40 Antigens
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Banchereau J
Schering-Plough Corporation, Laboratory for Immunological Research, Dardilly, France.
Rousset F
Article Info
Journal
Nature
Abbr.
Nature
ISSN
0028-0836
DOI
10.1038/353678a0
Published
1991-10-17
Pages
678-9
Language
English
Region
England
NLM ID
0410462
Subset
IM
External Links
PubMed source DOI: 10.1038/353678a0 View journal details
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