When is a heme transporter not a heme transporter? When it's a folate transporter.

Cell metabolism ·Vol. 5 ·No. 1 ·2007-01-00 ·Pages 5-6

Andrews NC

Abstract

Essential nutrients enter the body through a variety of specific transporter molecules expressed in the intestinal epithelium. A recent paper by elegantly demonstrates that one of these transporters, previously thought to carry heme, is in fact an important folate transporter.

MeSH Terms

Animals Anion Exchange Protein 1, Erythrocyte/metabolism Biological Transport HeLa Cells Heme/metabolism Humans Membrane Transport Proteins/metabolism Tetrahydrofolates/metabolism

Chemicals

Anion Exchange Protein 1, Erythrocyte Membrane Transport Proteins SLC4A1 protein, human Tetrahydrofolates Heme 5-methyltetrahydrofolate

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Andrews Nancy C

Children's Hospital Boston and Harvard Medical School, Boston, MA 02115, USA. [email protected]

Article Info

Journal

Cell metabolism

Abbr.

Cell Metab

ISSN

1550-4131

DOI

10.1016/j.cmet.2006.12.004

[email protected]

Published

2007-01-00

Pages

5-6

Language

English

Region

United States

NLM ID

101233170

Subset

Corrections

CommentOn

PMID: 17129779

External Links

PubMed source DOI: 10.1016/j.cmet.2006.12.004 View journal details

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When is a heme transporter not a heme transporter? When it's a folate transporter.

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