Operator-constitutive mutants in the threonine operon of Escherichia coli K-12.

Journal of bacteriology ·Vol. 124 ·No. 3 ·1975-12-00 ·Pages 1137-41

Saint-Girons I, Margarita D

Abstract

Three Escherichia coli K-12 mutant strains resistant to DL-alpha-amino-beta-hydroxyvaleric acid were isolated in which the expression of the thr operon is constitutive. The localization and dominance properties of the mutations involved, called thrO, are those of operator mutations. The gene sequence is OABC as suggested by earlier studies.

MeSH Terms

Aspartate Kinase/metabolism Cell-Free System Drug Resistance, Microbial Escherichia coli/drug effects,enzymology,metabolism Homoserine Homoserine Dehydrogenase/metabolism Lyases/metabolism Mutation Operon Phosphotransferases/metabolism Threonine/analogs & derivatives,biosynthesis,pharmacology Threonine Dehydratase/metabolism Transduction, Genetic

Chemicals

Threonine Homoserine Homoserine Dehydrogenase Phosphotransferases Aspartate Kinase Lyases Threonine Dehydratase

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Saint-Girons I

Margarita D

References (14)

14 references, click to expand

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Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.124.3.1137-1141.1975

Published

1975-12-00

Pages

1137-41

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC236018

Subset

External Links

PubMed source DOI: 10.1128/jb.124.3.1137-1141.1975 PMC Full Text View journal details

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Operator-constitutive mutants in the threonine operon of Escherichia coli K-12.

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