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PMID: 17359131 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Viscoelasticity of isotropically cross-linked actin networks.

Physical review letters ·Vol. 98 ·No. 8 ·2007-02-23 ·Pages 088103

Tharmann R, Claessens MM, Bausch AR

Abstract

Despite their importance for the proper function of living cells, the physical properties of cross-linked actin networks remain poorly understood as the occurrence of heterogeneities hamper a quantitative physical description. The isotropic homogeneously cross-linked actin network presented here enables us to quantitatively relate the network response to a single filament model by determining the dominating length scale. The frequency dependence of the linear response and nonuniversal form of the nonlinear response reveal the importance of cross-linker unbinding events.

MeSH Terms
Actin Cytoskeleton/chemistry Actins/chemistry Anisotropy Cross-Linking Reagents/chemistry Elasticity Models, Theoretical Viscosity
Chemicals
Actins Cross-Linking Reagents
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Tharmann R
E22-Biophysics, Technische Universität München, James Franck Strasse, 85748 Garching, Germany.
Claessens M M A E
Bausch A R
Article Info
Journal
Physical review letters
Abbr.
Phys Rev Lett
ISSN
0031-9007
Published
2007-02-23
Epub
2007-00-21
Pages
088103
Language
English
Region
United States
NLM ID
0401141
Subset
IM
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