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PMID: 175444 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S.

Angiotensin-converting enzyme: vascular endothelial localization.

Science (New York, N.Y.) ·Vol. 191 ·No. 4231 ·1976-03-12 ·Pages 1050-1

Caldwell PR, Seegal BC, Hsu KC, Das M, Soffer RL

Abstract

Fluorescein-labeled antibody to rabbit pulmonary angiotensin-converting enzyme localized in the vascular endothelium of rabbit lung, liver, adrenal cortex, pancreas, kidney, and spleen. Epithelial cells of the renal proximal tubules were the only parenchymal cells among the organs studied that demonstrated immunoreactivity.

MeSH Terms

Adrenal Cortex/blood supply Animals Blood Vessels/enzymology Endothelium/blood supply Fluorescent Antibody Technique Kidney/blood supply Liver/blood supply Lung/blood supply Pancreas/blood supply Peptidyl-Dipeptidase A/metabolism Rabbits Spleen/blood supply

Chemicals

Peptidyl-Dipeptidase A

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Caldwell P R

Seegal B C

Hsu K C

Das M

Soffer R L

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.175444

Published

1976-03-12

Pages

1050-1

Language

English

Region

United States

NLM ID

0404511

Subset

External Links

PubMed source DOI: 10.1126/science.175444 View journal details

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