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PMID: 17568814 Published · ppublish English Letter Research Support, Non-U.S. Gov't

Diagnostic evaluation of t(4;14) in multiple myeloma and evidence for clonal evolution.

Leukemia ·Vol. 21 ·No. 11 ·2007-11-00 ·Pages 2358-9

Stewart AK, Chang H, Trudel S, Anderson KC, Richardson P, Alsina M, Reece D, Young S, Sable-Hunt A, Li Z, Keats J, Van Wier S, Ahmann G, Price-Troska T, Giusti K, Bergsagel PL, Chesi M, Fonseca R

Abstract

暂无摘要

MeSH Terms
Bone Marrow Cells/metabolism Chromosomes, Human, Pair 14 Chromosomes, Human, Pair 4 Disease Progression Evolution, Molecular Flow Cytometry Humans Immunohistochemistry In Situ Hybridization, Fluorescence Multiple Myeloma/genetics Polymerase Chain Reaction Sensitivity and Specificity Translocation, Genetic Treatment Outcome
Authors & Affiliations
18 authors, click to expand affiliations / ORCID
Stewart A K
Chang H
Trudel S
Anderson K C
Richardson P
Alsina M
Reece D
Young S
Sable-Hunt A
Li Z
Keats J
Van Wier S
Ahmann G
Price-Troska T
Giusti K
Bergsagel P L
Chesi M
Fonseca R
References (8)
8 references, click to expand
  1. The t(4;14)(p16.3;q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance.
    Blood. 2001 Aug 15;98(4):1271-2 PMID: 11510469
  2. The t(4;14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant.
    Br J Haematol. 2004 Apr;125(1):64-8 PMID: 15015970
  3. CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma.
    Blood. 2005 Apr 1;105(7):2941-8 PMID: 15598814
  4. Genetic abnormalities and survival in multiple myeloma: the experience of the Intergroupe Francophone du Myélome.
    Blood. 2007 Apr 15;109(8):3489-95 PMID: 17209057
  5. Immunohistochemistry accurately predicts FGFR3 aberrant expression and t(4;14) in multiple myeloma.
    Blood. 2005 Jul 1;106(1):353-5 PMID: 15761022
  6. The molecular classification of multiple myeloma.
    Blood. 2006 Sep 15;108(6):2020-8 PMID: 16728703
  7. Detection and follow-up of fibroblast growth factor receptor 3 expression on bone marrow and circulating plasma cells by flow cytometry in patients with t(4;14) multiple myeloma.
    Br J Haematol. 2007 Feb;136(4):609-14 PMID: 17223917
  8. Overexpression of transcripts originating from the MMSET locus characterizes all t(4;14)(p16;q32)-positive multiple myeloma patients.
    Blood. 2005 May 15;105(10):4060-9 PMID: 15677557
Article Info
Journal
Leukemia
Abbr.
Leukemia
ISSN
0887-6924
DOI
10.1038/sj.leu.2404800
Published
2007-11-00
Epub
2007-00-14
Pages
2358-9
Language
English
Region
England
NLM ID
8704895
PMCID
PMC3882151
Subset
IM
Grants
NCI NIH HHS · P50 CA100707 · United States
NCI NIH HHS · P50 CA100707-010005 · United States
NCI NIH HHS · R01 CA083724 · United States
NCI NIH HHS · R01 CA083724-01 · United States
External Links
PubMed source DOI: 10.1038/sj.leu.2404800 PMC Full Text View journal details
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