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PMID: 17657473 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Comment

Analysis of the obesity gene FTO in 14,803 type 1 diabetes cases and controls.

Diabetologia ·Vol. 50 ·No. 10 ·2007-10-00 ·Pages 2218-20

Field SF, Howson JM, Walker NM, Dunger DB, Todd JA

Abstract

暂无摘要

MeSH Terms

Alpha-Ketoglutarate-Dependent Dioxygenase FTO Chromosome Mapping Chromosomes, Human, Pair 16 Diabetes Mellitus, Type 1/genetics Diabetes Mellitus, Type 2/genetics Genetic Predisposition to Disease Humans Obesity/genetics Proteins/genetics Reference Values

Chemicals

Proteins Alpha-Ketoglutarate-Dependent Dioxygenase FTO FTO protein, human

Authors & Affiliations

5 authors, click to expand affiliations / ORCID

Field S F

Howson J M M

Walker N M

Dunger D B

Todd J A

References (8)

8 references, click to expand

Growth during childhood and final height in type 1 diabetes.
Diabet Med. 1994 Mar;11(2):182-7 PMID: 8200204
Rapid early growth is associated with increased risk of childhood type 1 diabetes in various European populations.
Diabetes Care. 2002 Oct;25(10):1755-60 PMID: 12351473
Nutritional risk predictors of beta cell autoimmunity and type 1 diabetes at a young age.
Am J Clin Nutr. 2003 Dec;78(6):1053-67 PMID: 14668264
A high weight gain early in life is associated with an increased risk of type 1 (insulin-dependent) diabetes mellitus.
Diabetologia. 1994 Jan;37(1):91-4 PMID: 8150235
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls.
Nature. 2007 Jun 7;447(7145):661-78 PMID: 17554300
Diet, growth, and the risk for type 1 diabetes in childhood: a matched case-referent study.
Diabetes Care. 2004 Dec;27(12):2784-9 PMID: 15562185
Longitudinal relation between limited joint mobility, height, insulin-like growth factor 1 levels, and risk of developing microalbuminuria: the Oxford Regional Prospective Study.
Arch Dis Child. 2005 Oct;90(10):1039-44 PMID: 16177159
A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity.
Science. 2007 May 11;316(5826):889-94 PMID: 17434869

Article Info

Journal

Diabetologia

Abbr.

Diabetologia

ISSN

0012-186X

DOI

10.1007/s00125-007-0767-0

Published

2007-10-00

Epub

2007-00-27

Pages

2218-20

Language

English

Region

Germany

NLM ID

0006777

PMCID

PMC2151140

Subset

Grants

Wellcome Trust · 061858 · United Kingdom

Medical Research Council · G0000934 · United Kingdom

Wellcome Trust · 068545/Z/02 · United Kingdom

Corrections

CommentOn

PMID: 8150235

External Links

PubMed source DOI: 10.1007/s00125-007-0767-0 PMC Full Text View journal details

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Analysis of the obesity gene FTO in 14,803 type 1 diabetes cases and controls.

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