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PMID: 17693249 Published · ppublish English

Fetal to adult stem cell transition: knocking Sox17 off.

Cell ·Vol. 130 ·No. 3 ·2007-09-18

Jang Yoon-Young, Sharkis Saul J

Abstract

What controls the inherent differences between fetal and adult hematopoietic stem cells (HSCs)? In this issue of Cell, Kim et al. (2007) demonstrate in mice that the endodermal transcription factor Sox17 is required for the maintenance of fetal and neonatal but not adult HSCs.

Article Info
Journal
Cell
Abbr.
Cell
ISSN
0092-8674
DOI
10.1016/j.cell.2007.07.027
Published
2007-09-18
Indexed
2007-08-13
Updated
2008-11-21
Language
English
Country/Region
United States
NLM ID
0413066
External Links
PubMed source DOI: 10.1016/j.cell.2007.07.027 View journal details
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