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PMID: 177173 Published · ppublish English Journal Article

Morphologic study of virus-like particles in a case of acute leukemia.

Cancer ·Vol. 37 ·No. 4 ·1976-04-00 ·Pages 1718-24

Foa C, Foa J, Carcassonne Y

Abstract

Virus-like particles, grouped in clusters not bound by a membraine, were seen in electron micrographs of fresh leucoblasts of an acute leukemic patient. They consisted of large (100-nm diameter), round particles apparently composed of subunits. Tubular structures (30-50-nm diameter) were also seen in leucoblasts of the same patient. The two types of structures were never seen simultaneously in the same cell. The authors review the literature pertaining to the morphology of virus-like particles associated with malignant hematologic disease.

MeSH Terms
Cell Nucleolus/ultrastructure Cell Nucleus/ultrastructure Chromatin/ultrastructure Cytoplasm/ultrastructure Humans Inclusion Bodies/ultrastructure Inclusion Bodies, Viral/ultrastructure Leukemia, Lymphoid/pathology Membranes/ultrastructure Mitochondria/ultrastructure
Chemicals
Chromatin
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Foa C
Foa J
Carcassonne Y
References (26)
26 references, click to expand
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Article Info
Journal
Cancer
Abbr.
Cancer
ISSN
0008-543X
DOI
10.1002/1097-0142(197604)37:4<1718::aid-cncr2820370417>3.0.co;2-x
Published
1976-04-00
Pages
1718-24
Language
English
Region
United States
NLM ID
0374236
PMCID
PMC7162349
Subset
IM
External Links
PubMed source DOI: 10.1002/1097-0142(197604)37:4<1718::aid-cncr2820370417>3.0.co;2-x PMC Full Text View journal details
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