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PMID: 17770204 Published · ppublish English Journal Article

BACITRACIN: A NEW ANTIBIOTIC PRODUCED BY A MEMBER OF THE B. SUBTILIS GROUP.

Science (New York, N.Y.) ·Vol. 102 ·No. 2650 ·1945-10-12 ·Pages 376-7

Johnson BA, Anker H, Meleney FL

Abstract

A new antibiotic "bacitracin" has been recovered from a strain of the B. subtilis group of organisms. It is neutral, water-soluble, non-toxic and relatively heat stable. In vitro it is active chiefly against Grampositive organisms, but the gonococcus and meningococcus are susceptible to its action. It is also active in vivo against experimentally produced hemolytic streptococcal infections in mice and gas gangrene infections in guinea pigs. Clinical use in hemolytic streptococcal and staphylococcal infections in man have given encouraging results.

Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Johnson B A
Anker H
Meleney F L
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
0036-8075
Published
1945-10-12
Pages
376-7
Language
English
Region
United States
NLM ID
0404511
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