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PMID: 17906673 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Review

Artery and vein formation: a tug of war between different forces.

EMBO reports ·Vol. 8 ·No. 10 ·2007-10-00 ·Pages 920-4

Lin FJ, Tsai MJ, Tsai SY

Abstract

How arterial and venous fates are established is largely unknown. In the past, circulatory dynamics were thought to be the exclusive cause of arteries and veins being structurally and functionally distinct; however, growing evidence indicates that an orderly progression of molecular signals controls arterial-venous specification in the developing vertebrate vascular system.

MeSH Terms
Animals Arteries/embryology COUP Transcription Factor II/metabolism Forkhead Transcription Factors/metabolism Hedgehog Proteins/metabolism Humans Models, Biological Neovascularization, Physiologic Veins/embryology
Chemicals
COUP Transcription Factor II Forkhead Transcription Factors Hedgehog Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Lin Fu-Jung
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
Tsai Ming-Jer
Tsai Sophia Y
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Article Info
Journal
EMBO reports
Abbr.
EMBO Rep
ISSN
1469-221X
DOI
10.1038/sj.embor.7401076
Published
2007-10-00
Pages
920-4
Language
English
Region
England
NLM ID
100963049
PMCID
PMC2002564
Subset
IM
Grants
NICHD NIH HHS · R37 HD017379 · United States
NICHD NIH HHS · HD17379 · United States
NIDDK NIH HHS · P01 DK059820 · United States
NIDDK NIH HHS · R01 DK045641 · United States
NHLBI NIH HHS · R01 HL076448 · United States
NICHD NIH HHS · R01 HD017379 · United States
NIDDK NIH HHS · R37 DK045641 · United States
NIDDK NIH HHS · DK59820 · United States
NHLBI NIH HHS · HL076448 · United States
NIDDK NIH HHS · DK45641 · United States
External Links
PubMed source DOI: 10.1038/sj.embor.7401076 PMC Full Text View journal details
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