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PMID: 17978276 Published · ppublish English Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Association between genetic variants in SORL1 and autopsy-confirmed Alzheimer disease.

Neurology ·Vol. 70 ·No. 11 ·2008-03-11 ·Pages 887-9

Lee JH, Cheng R, Honig LS, Vonsattel JP, Clark L, Mayeux R

Abstract

暂无摘要

MeSH Terms

Aged Aged, 80 and over Alzheimer Disease/genetics,pathology Autopsy Cohort Studies Female Genetic Variation/genetics Humans LDL-Receptor Related Proteins/genetics Male Membrane Transport Proteins/genetics Polymorphism, Single Nucleotide/genetics Prospective Studies

Chemicals

LDL-Receptor Related Proteins Membrane Transport Proteins SORL1 protein, human

Authors & Affiliations

6 authors, click to expand affiliations / ORCID

Lee J H

Gertrude H. Sergievsky Center, Columbia University, 630 W. 168 St., New York, NY 10032, USA.

Cheng R

Honig L S

Vonsattel J-P G

Clark L

Mayeux R

References (10)

10 references, click to expand

Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme.
J Neurosci. 2006 Jan 11;26(2):418-28 PMID: 16407538
The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments.
J Neurosci. 2006 Feb 1;26(5):1596-603 PMID: 16452683
Molecular dissection of the interaction between amyloid precursor protein and its neuronal trafficking receptor SorLA/LR11.
Biochemistry. 2006 Feb 28;45(8):2618-28 PMID: 16489755
Neuronal sorting protein-related receptor sorLA/LR11 regulates processing of the amyloid precursor protein.
Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13461-6 PMID: 16174740
Haploview: analysis and visualization of LD and haplotype maps.
Bioinformatics. 2005 Jan 15;21(2):263-5 PMID: 15297300
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease.
Nat Genet. 2007 Feb;39(2):168-77 PMID: 17220890
Diagnosis of dementia in a heterogeneous population. Development of a neuropsychological paradigm-based diagnosis of dementia and quantified correction for the effects of education.
Arch Neurol. 1992 May;49(5):453-60 PMID: 1580806
Diagnosis of dementia in a heterogeneous population. A comparison of paradigm-based diagnosis and physician's diagnosis.
Arch Neurol. 1992 May;49(5):461-7 PMID: 1580807
The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort.
Arch Neurol. 2007 Apr;64(4):501-6 PMID: 17420311
Normative data for a brief neuropsychological battery administered to English- and Spanish-speaking community-dwelling elders.
J Int Neuropsychol Soc. 1998 Jul;4(4):311-8 PMID: 9656604

Article Info

Journal

Neurology

Abbr.

Neurology

ISSN

1526-632X

DOI

10.1212/01.wnl.0000280581.39755.89

Published

2008-03-11

Epub

2007-00-31

Pages

887-9

Language

English

Region

United States

NLM ID

0401060

PMCID

PMC2634845

Subset

Grants

NIA NIH HHS · R37 AG015473-10 · United States

NIA NIH HHS · P50 AG008702 · United States

NIA NIH HHS · P01 AG007232 · United States

NIA NIH HHS · R37 AG015473 · United States

NIA NIH HHS · R37-AG15473 · United States

NIA NIH HHS · R37 AG015473-07 · United States

NIA NIH HHS · P50-AG08702 · United States

NIA NIH HHS · R37 AG015473-09 · United States

NIA NIH HHS · P01-AG07232 · United States

NIA NIH HHS · R37 AG015473-08 · United States

External Links

PubMed source DOI: 10.1212/01.wnl.0000280581.39755.89 PMC Full Text View journal details

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Association between genetic variants in SORL1 and autopsy-confirmed Alzheimer disease.

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