Abstract
GenBank (R) is a comprehensive database that contains publicly available nucleotide sequences for more than 260 000 named organisms, obtained primarily through submissions from individual laboratories and batch submissions from large-scale sequencing projects. Most submissions are made using the web-based BankIt or standalone Sequin programs and accession numbers are assigned by GenBank staff upon receipt. Daily data exchange with the European Molecular Biology Laboratory Nucleotide Sequence Database in Europe and the DNA Data Bank of Japan ensures worldwide coverage. GenBank is accessible through NCBI's retrieval system, Entrez, which integrates data from the major DNA and protein sequence databases along with taxonomy, genome, mapping, protein structure and domain information, and the biomedical journal literature via PubMed. BLAST provides sequence similarity searches of GenBank and other sequence databases. Complete bimonthly releases and daily updates of the GenBank database are available by FTP. To access GenBank and its related retrieval and analysis services, begin at the NCBI Homepage: www.ncbi.nlm.nih.gov.
MeSH Terms
DNA, Complementary/chemistry
Databases, Nucleic Acid
Expressed Sequence Tags/chemistry
Genomics
Internet
National Library of Medicine (U.S.)
Sequence Analysis, DNA
United States
User-Computer Interface
Chemicals
DNA, Complementary
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Benson Dennis A
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA.
Karsch-Mizrachi Ilene
Lipman David J
Ostell James
Wheeler David L
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