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PMID: 18270734 Published · ppublish English Journal Article

School functioning in 8- to 18-year-old children born after in vitro fertilization.

European journal of pediatrics ·Vol. 167 ·No. 11 ·2008-11-00 ·Pages 1289-95

Wagenaar K, Ceelen M, van Weissenbruch MM, Knol DL, Delemarre-van de Waal HA, Huisman J

Abstract

The aim of this study was to examine the school functioning of 8- to 18-year-old children born after in vitro fertilization (IVF). We compared 233 children born after IVF to 233 matched control children born spontaneously from parents with fertility problems on measures of education level, general cognitive ability, school performance (need for extra help, repeating a grade, special education), and rates of learning and developmental disorders. No differences were found between IVF and control children on these measures of school functioning. More than 60% of adolescents at secondary school attended high academic levels (with access to high school or university). We conclude that children and adolescents born after IVF show good academic achievement and general cognitive ability. They do not experience any more educational limitations than the naturally conceived children and adolescents of the control group. The tendency of reassuring school functioning already found in younger IVF children has been shown to continue at secondary school age.

MeSH Terms
Achievement Adolescent Child Cognition Developmental Disabilities/epidemiology Female Fertilization in Vitro/statistics & numerical data Humans Learning Disabilities/epidemiology Male Pregnancy Prevalence
Authors & Affiliations
6 authors, click to expand affiliations / ORCID
Wagenaar Karin
Department of Medical Psychology and Institute for Clinical and Experimental Neurosciences, VU University Medical Center, Amsterdam, The Netherlands. [email protected]
Ceelen Manon
van Weissenbruch Mirjam M
Knol Dirk L
Delemarre-van de Waal Henriette A
Huisman Jaap
References (25)
25 references, click to expand
  1. Body composition in children and adolescents born after in vitro fertilization or spontaneous conception.
    J Clin Endocrinol Metab. 2007 Sep;92(9):3417-23 PMID: 17595253
  2. Perinatal outcome and developmental studies on children born after IVF.
    Hum Reprod Update. 2002 Mar-Apr;8(2):117-28 PMID: 12099627
  3. Post-neonatal health and development of children born after assisted reproduction: a systematic review of controlled studies.
    Eur J Obstet Gynecol Reprod Biol. 2006 Jul;127(1):3-25 PMID: 16621225
  4. International collaborative study of intracytoplasmic sperm injection-conceived, in vitro fertilization-conceived, and naturally conceived 5-year-old child outcomes: cognitive and motor assessments.
    Pediatrics. 2005 Mar;115(3):e283-9 PMID: 15741353
  5. A prospective longitudinal study of the physical, psychomotor, and intellectual development of singleton children up to 5 years who were conceived by intracytoplasmic sperm injection compared with children conceived spontaneously and by in vitro fertilization.
    Fertil Steril. 2003 Dec;80(6):1388-97 PMID: 14667874
  6. Postnatal growth and health in children born after cryopreservation as embryos.
    Lancet. 1998 Apr 11;351(9109):1085-90 PMID: 9660577
  7. Comparative prospective study of the psychological development of children born by in vitro fertilization and their mothers.
    J Psychosom Obstet Gynaecol. 1993 Jun;14(2):117-26 PMID: 8358525
  8. Children after in vitro fertilization. An overview of the literature.
    Int J Technol Assess Health Care. 1999 Winter;15(1):52-65 PMID: 10407596
  9. Perinatal outcome and follow-up of 82 children aged 1-9 years old conceived from cryopreserved embryos.
    Hum Reprod. 1996 Jul;11(7):1565-8 PMID: 8671505
  10. Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies.
    BMJ. 2004 Jan 31;328(7434):261 PMID: 14742347
  11. Psychological follow-up of children born after in-vitro fertilization.
    Hum Reprod. 1994 Jun;9(6):1097-101 PMID: 7962382
  12. In vitro fertilization children: early psychosocial development.
    J In Vitro Fert Embryo Transf. 1986 Aug;3(4):247-52 PMID: 3760660
  13. Development of children born after ovarian superovulation induced by long-acting gonadotropin-releasing hormone agonist and menotropins, and by in vitro fertilization.
    J Pediatr. 1994 Nov;125(5 Pt 1):734-7 PMID: 7525915
  14. Growth, psychomotor development and morbidity up to 3 years of age in children born after IVF.
    Hum Reprod. 2003 Nov;18(11):2328-36 PMID: 14585883
  15. Minor congenital anomalies, major congenital malformations and development in children conceived from cryopreserved embryos.
    Hum Reprod. 1995 Dec;10(12):3332-7 PMID: 8822471
  16. The physical and psychomotor development of children conceived by IVF and exposed to high-frequency vaginal ultrasonography (6.5 MHz) in the first trimester of pregnancy.
    Ultrasound Obstet Gynecol. 1991 Jan 1;1(1):21-8 PMID: 12797098
  17. Follow-up of a cohort of 422 children aged 6 to 13 years conceived by in vitro fertilization.
    Fertil Steril. 1997 Feb;67(2):284-9 PMID: 9022604
  18. Medical, cognitive, emotional, and behavioral outcomes in school-age children conceived by in-vitro fertilization.
    J Clin Child Psychol. 1998 Oct;27(3):320-9 PMID: 9789191
  19. Intelligence and behaviour in children born after in-vitro fertilization treatment.
    Hum Reprod. 1996 Sep;11(9):2052-7 PMID: 8921089
  20. Birth after the reimplantation of a human embryo.
    Lancet. 1978 Aug 12;2(8085):366 PMID: 79723
  21. Children conceived using ICSI do not have an increased risk of delayed mental development at 5 years of age.
    Hum Reprod. 2003 Oct;18(10):2067-72 PMID: 14507822
  22. Congenital malformations and psychosocial development in children conceived by in vitro fertilization.
    J Pediatr. 1989 Aug;115(2):222-7 PMID: 2666626
  23. Development, behaviour and temperament: a prospective study of infants conceived through in-vitro fertilization.
    Hum Reprod. 1998 Jun;13(6):1727-32 PMID: 9688422
  24. Growth and development of children conceived by in vitro fertilization.
    Pediatrics. 1992 Sep;90(3):424-9 PMID: 1518701
  25. Heritability of educational achievement in 12-year-olds and the overlap with cognitive ability.
    Twin Res. 2002 Dec;5(6):544-53 PMID: 12573186
Article Info
Journal
European journal of pediatrics
Abbr.
Eur J Pediatr
ISSN
1432-1076
Published
2008-11-00
Epub
2008-00-13
Pages
1289-95
Language
English
Region
Germany
NLM ID
7603873
Subset
IM
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