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PMID: 18371356 Published · ppublish English Journal Article Comment

Cancer stem cells and tumor metastasis: first steps into uncharted territory.

Cell stem cell ·Vol. 1 ·No. 3 ·2007-09-13 ·Pages 241-2

Dalerba P, Clarke MF

Abstract

In several forms of human cancer, only a phenotypic subset of cancer cells, usually termed "cancer stem cells" (CSC), can initiate tumor growth when transplanted. In this issue of Cell Stem Cell, Hermann et al. (2007) analyze the relationship between CSC and tumor metastasis.

MeSH Terms
AC133 Antigen Animals Antigens, CD/metabolism Cell Movement Cell Proliferation Glycoproteins/metabolism Humans Mice Neoplasm Metastasis Neoplastic Stem Cells/pathology Pancreatic Neoplasms/pathology Peptides/metabolism Receptors, CXCR4/metabolism
Chemicals
AC133 Antigen Antigens, CD Glycoproteins Peptides Receptors, CXCR4
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Dalerba Piero
Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Palo Alto, CA 94304, USA.
Clarke Michael F
Article Info
Journal
Cell stem cell
Abbr.
Cell Stem Cell
ISSN
1875-9777
DOI
10.1016/j.stem.2007.08.012
Published
2007-09-13
Pages
241-2
Language
English
Region
United States
NLM ID
101311472
Subset
IM
Corrections
CommentOn
PMID: 18371365
External Links
PubMed source DOI: 10.1016/j.stem.2007.08.012 View journal details
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