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PMID: 18483219 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Control of final seed and organ size by the DA1 gene family in Arabidopsis thaliana.

Genes & development ·Vol. 22 ·No. 10 ·2008-05-15 ·Pages 1331-6

Li Y, Zheng L, Corke F, Smith C, Bevan MW

Abstract

Although the size of an organism is a defining feature, little is known about the mechanisms that set the final size of organs and whole organisms. Here we describe Arabidopsis DA1, encoding a predicted ubiquitin receptor, which sets final seed and organ size by restricting the period of cell proliferation. The mutant protein encoded by the da1-1 allele has a negative activity toward DA1 and a DA1-related (DAR) protein, and overexpression of a da1-1 cDNA dramatically increases seed and organ size of wild-type plants, identifying this small gene family as important regulators of seed and organ size in plants.

MeSH Terms
Arabidopsis/genetics,growth & development Arabidopsis Proteins/genetics,physiology Cloning, Molecular DNA, Complementary/genetics,physiology Enhancer Elements, Genetic Flowers/genetics,growth & development Gene Expression Regulation, Plant Genes, Plant/physiology Germination/genetics LIM Domain Proteins Multigene Family/physiology Organ Size/genetics Plants, Genetically Modified Promoter Regions, Genetic Receptors, Cell Surface/genetics,physiology Seeds/growth & development
Chemicals
Arabidopsis Proteins DA1 protein, Arabidopsis DNA, Complementary LIM Domain Proteins Receptors, Cell Surface
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Li Yunhai
Department of Cell and Developmental Biology, John Innes Centre, Norwich NR4 7UH, United Kingdom. [email protected]
Zheng Leiying
Corke Fiona
Smith Caroline
Bevan Michael W
References (38)
38 references, click to expand
  1. PEAPOD regulates lamina size and curvature in Arabidopsis.
    Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13238-43 PMID: 16916932
  2. Regulation and function of the Arabidopsis ABA-insensitive4 gene in seed and abscisic acid response signaling networks.
    Plant Physiol. 2000 Dec;124(4):1752-65 PMID: 11115891
  3. Seed-specific immunomodulation of abscisic acid activity induces a developmental switch.
    EMBO J. 1997 Aug 1;16(15):4489-96 PMID: 9303293
  4. A postgermination developmental arrest checkpoint is mediated by abscisic acid and requires the ABI5 transcription factor in Arabidopsis.
    Proc Natl Acad Sci U S A. 2001 Apr 10;98(8):4782-7 PMID: 11287670
  5. Size control in animal development.
    Cell. 1999 Jan 22;96(2):235-44 PMID: 9988218
  6. BIGPETALp, a bHLH transcription factor is involved in the control of Arabidopsis petal size.
    EMBO J. 2006 Aug 23;25(16):3912-20 PMID: 16902407
  7. LIM domains: multiple roles as adapters and functional modifiers in protein interactions.
    Trends Genet. 1998 Apr;14(4):156-62 PMID: 9594664
  8. Crystal structure of the ubiquitin binding domains of rabex-5 reveals two modes of interaction with ubiquitin.
    Cell. 2006 Mar 24;124(6):1183-95 PMID: 16499958
  9. Establishing glucose- and ABA-regulated transcription networks in Arabidopsis by microarray analysis and promoter classification using a Relevance Vector Machine.
    Genome Res. 2006 Mar;16(3):414-27 PMID: 16424108
  10. Ubiquitin-binding domains.
    Biochem J. 2006 Nov 1;399(3):361-72 PMID: 17034365
  11. Control of seed mass by APETALA2.
    Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):3123-8 PMID: 15708976
  12. Ectopic expression of AINTEGUMENTA in Arabidopsis plants results in increased growth of floral organs.
    Dev Genet. 1999 Sep;25(3):224-36 PMID: 10528263
  13. "Big it up": endoreduplication and cell-size control in plants.
    Curr Opin Plant Biol. 2003 Dec;6(6):544-53 PMID: 14611952
  14. The AUXIN RESPONSE FACTOR 2 gene of Arabidopsis links auxin signalling, cell division, and the size of seeds and other organs.
    Development. 2006 Jan;133(2):251-61 PMID: 16339187
  15. The Arabidopsis auxin-inducible gene ARGOS controls lateral organ size.
    Plant Cell. 2003 Sep;15(9):1951-61 PMID: 12953103
  16. Genetic control of surface curvature.
    Science. 2003 Feb 28;299(5611):1404-7 PMID: 12610308
  17. A novel two-component hybrid molecule regulates vascular morphogenesis of the Arabidopsis root.
    Genes Dev. 2000 Dec 1;14(23):2938-43 PMID: 11114883
  18. A unique short-chain dehydrogenase/reductase in Arabidopsis glucose signaling and abscisic acid biosynthesis and functions.
    Plant Cell. 2002 Nov;14(11):2723-43 PMID: 12417697
  19. The role of JAGGED in shaping lateral organs.
    Development. 2004 Mar;131(5):1101-10 PMID: 14973282
  20. Plant organ size control: AINTEGUMENTA regulates growth and cell numbers during organogenesis.
    Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):942-7 PMID: 10639184
  21. Cytokinins regulate a bidirectional phosphorelay network in Arabidopsis.
    Curr Biol. 2006 Jun 6;16(11):1116-22 PMID: 16753566
  22. Control of seed mass and seed yield by the floral homeotic gene APETALA2.
    Proc Natl Acad Sci U S A. 2005 Feb 22;102(8):3117-22 PMID: 15708974
  23. Ubiquitin-binding domains.
    Nat Rev Mol Cell Biol. 2005 Aug;6(8):610-21 PMID: 16064137
  24. Abscisic acid signaling in seeds and seedlings.
    Plant Cell. 2002;14 Suppl:S15-45 PMID: 12045268
  25. Maternal control of integument cell elongation and zygotic control of endosperm growth are coordinated to determine seed size in Arabidopsis.
    Plant Cell. 2005 Jan;17(1):52-60 PMID: 15598800
  26. Elucidation of a universal size-control mechanism in Drosophila and mammals.
    Cell. 2007 Sep 21;130(6):1120-33 PMID: 17889654
  27. Measuring dimensions: the regulation of size and shape.
    Development. 2000 Jul;127(14):2977-87 PMID: 10862736
  28. Cell cycling and cell enlargement in developing leaves of Arabidopsis.
    Dev Biol. 1999 Nov 15;215(2):407-19 PMID: 10545247
  29. Growth and development of the axr1 mutants of Arabidopsis.
    Plant Cell. 1990 Nov;2(11):1071-80 PMID: 1983791
  30. The transcription factor AtGRF5 and the transcription coactivator AN3 regulate cell proliferation in leaf primordia of Arabidopsis thaliana.
    Plant J. 2005 Jul;43(1):68-78 PMID: 15960617
  31. Novel cysteine-rich motif and homeodomain in the product of the Caenorhabditis elegans cell lineage gene lin-11.
    Nature. 1990 Apr 26;344(6269):876-9 PMID: 1970421
  32. The E3 ubiquitin ligase BIG BROTHER controls arabidopsis organ size in a dosage-dependent manner.
    Curr Biol. 2006 Feb 7;16(3):272-9 PMID: 16461280
  33. Recessive-interfering mutations in the gibberellin signaling gene SLEEPY1 are rescued by overexpression of its homologue, SNEEZY.
    Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12771-6 PMID: 15308775
  34. Arabidopsis haiku mutants reveal new controls of seed size by endosperm.
    Plant Physiol. 2003 Apr;131(4):1661-70 PMID: 12692325
  35. The LIM domain: from the cytoskeleton to the nucleus.
    Nat Rev Mol Cell Biol. 2004 Nov;5(11):920-31 PMID: 15520811
  36. Convergence of signaling pathways in the control of differential cell growth in Arabidopsis.
    Dev Cell. 2004 Aug;7(2):193-204 PMID: 15296716
  37. Interaction of hHR23 with S5a. The ubiquitin-like domain of hHR23 mediates interaction with S5a subunit of 26 S proteasome.
    J Biol Chem. 1999 Sep 24;274(39):28019-25 PMID: 10488153
  38. Mechanism of leaf-shape determination.
    Annu Rev Plant Biol. 2006;57:477-96 PMID: 16669771
Article Info
Journal
Genes & development
Abbr.
Genes Dev
ISSN
0890-9369
DOI
10.1101/gad.463608
Email
[email protected]
Published
2008-05-15
Pages
1331-6
Language
English
Region
United States
NLM ID
8711660
PMCID
PMC2377187
Subset
IM
External Links
PubMed source DOI: 10.1101/gad.463608 PMC Full Text View journal details
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