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PMID: 18598378 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Review

What makes pathogens pathogenic.

Genome biology ·Vol. 9 ·No. 6 ·2008-00-00 ·Pages 225

Ehrlich GD, Hiller NL, Hu FZ

Abstract

Metazoans contain multiple complex microbial ecosystems in which the balance between host and microbe can be tipped from commensalism to pathogenicity. This transition is likely to depend both on the prevailing environmental conditions and on specific gene-gene interactions placed within the context of the entire ecosystem.

MeSH Terms
Animals Bacteria/classification,genetics,pathogenicity Host-Pathogen Interactions Humans Mutation Virulence
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Ehrlich Garth D
Center for Genomic Sciences, Allegheny General Hospital, Allegheny Singer Research Institute, Pittsburgh, PA 15212, USA. [email protected]
Hiller N Luisa
Hu Fen Ze
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Article Info
Journal
Genome biology
Abbr.
Genome Biol
ISSN
1474-760X
DOI
10.1186/gb-2008-9-6-225
Email
[email protected]
Published
2008-00-00
Epub
2008-00-24
Pages
225
Language
English
Region
England
NLM ID
100960660
PMCID
PMC2481411
Subset
IM
Grants
NIDCD NIH HHS · R01 DC004173 · United States
NIDCD NIH HHS · R01 DC002148 · United States
NIDCD NIH HHS · R01 DC005659 · United States
NIDCD NIH HHS · DC05659 · United States
NIDCD NIH HHS · DC04173 · United States
NIDCD NIH HHS · DC02148 · United States
External Links
PubMed source DOI: 10.1186/gb-2008-9-6-225 PMC Full Text View journal details
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