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PMID: 18772429 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Shadow enhancers as a source of evolutionary novelty.

Science (New York, N.Y.) ·Vol. 321 ·No. 5894 ·2008-09-05 ·Pages 1314

Hong JW, Hendrix DA, Levine MS

Abstract

暂无摘要

MeSH Terms
Animals Binding Sites Body Patterning/genetics Chromatin Immunoprecipitation Computational Biology Drosophila/embryology,genetics Drosophila Proteins/metabolism Drosophila melanogaster/embryology,genetics Embryonic Development Enhancer Elements, Genetic Evolution, Molecular Gene Expression Regulation, Developmental Introns Nuclear Proteins/metabolism Oligonucleotide Array Sequence Analysis Phosphoproteins/metabolism Phylogeny Transcription Factors/metabolism
Chemicals
Drosophila Proteins Nuclear Proteins Phosphoproteins Transcription Factors dl protein, Drosophila
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hong Joung-Woo
Department of Molecular and Cell Biology, Division of Genetics, Genomics, and Development, Center for Integrative Genomics, University of California, Berkeley, CA 94720, USA.
Hendrix David A
Levine Michael S
References (6)
6 references, click to expand
  1. A functional screen for sonic hedgehog regulatory elements across a 1 Mb interval identifies long-range ventral forebrain enhancers.
    Development. 2006 Feb;133(4):761-72 PMID: 16407397
  2. Whole-genome ChIP-chip analysis of Dorsal, Twist, and Snail suggests integration of diverse patterning processes in the Drosophila embryo.
    Genes Dev. 2007 Feb 15;21(4):385-90 PMID: 17322397
  3. The evolution of gene regulation underlies a morphological difference between two Drosophila sister species.
    Cell. 2008 Mar 7;132(5):783-93 PMID: 18329365
  4. Genome-wide analysis of clustered Dorsal binding sites identifies putative target genes in the Drosophila embryo.
    Proc Natl Acad Sci U S A. 2002 Jan 22;99(2):763-8 PMID: 11752406
  5. Redundant and unique roles of two enhancer elements in the TCRgamma locus in gene regulation and gammadelta T cell development.
    Immunity. 2002 Mar;16(3):453-63 PMID: 11911829
  6. Whole-genome analysis of dorsal-ventral patterning in the Drosophila embryo.
    Cell. 2002 Nov 27;111(5):687-701 PMID: 12464180
Article Info
Journal
Science (New York, N.Y.)
Abbr.
Science
ISSN
1095-9203
DOI
10.1126/science.1160631
Published
2008-09-05
Pages
1314
Language
English
Region
United States
NLM ID
0404511
PMCID
PMC4257485
Subset
IM
Grants
NIGMS NIH HHS · R01 GM046638 · United States
NIGMS NIH HHS · GM46638 · United States
Corrections
CommentIn
PMID: 18772422
External Links
PubMed source DOI: 10.1126/science.1160631 PMC Full Text View journal details
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