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PMID: 1879950 Published · ppublish English Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Purification and characterization of Helicobacter mustelae urease.

Infection and immunity ·Vol. 59 ·No. 9 ·1991-09-00 ·Pages 3343-5

Dunn BE, Sung CC, Taylor NS, Fox JG

Abstract

Helicobacter mustelae is a urease-rich bacterium associated with gastritis in ferrets. The ureases of H. mustelae and Helicobacter pylori, a bacterium implicated in human gastritis, share many characteristics. Helicobacter sp. ureases appear to be unique among bacterial enzymes in exhibiting submillimolar Km values and in being composed of two subunits.

MeSH Terms
Campylobacter/enzymology Chromatography, Gel Chromatography, High Pressure Liquid Electrophoresis, Polyacrylamide Gel Helicobacter pylori/enzymology Molecular Weight Urease/chemistry,isolation & purification
Chemicals
Urease
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Dunn B E
Laboratory Service, John L. McClellan Memorial Veterans Hospital, Little Rock, Arkansas.
Sung C C
Taylor N S
Fox J G
References (23)
23 references, click to expand
  1. Helicobacter mustelae-induced gastritis and elevated gastric pH in the ferret (Mustela putorius furo).
    Infect Immun. 1991 Jun;59(6):1875-80 PMID: 2037349
  2. Purification and N-terminal analysis of urease from Helicobacter pylori.
    Infect Immun. 1990 Apr;58(4):992-8 PMID: 2318539
  3. Helicobacter pylori and peptic ulcer disease.
    N Engl J Med. 1991 Apr 11;324(15):1043-8 PMID: 2005942
  4. Shuttle cloning and nucleotide sequences of Helicobacter pylori genes responsible for urease activity.
    J Bacteriol. 1991 Mar;173(6):1920-31 PMID: 2001995
  5. Investigation of the structure and localization of the urease of Helicobacter pylori using monoclonal antibodies.
    J Gen Microbiol. 1990 Oct;136(10):1995-2000 PMID: 2269872
  6. Campylobacter pyloridis, urease, hydrogen ion back diffusion, and gastric ulcers.
    Lancet. 1986 Jul 5;2(8497):15-7 PMID: 2873317
  7. Microbial ureases: significance, regulation, and molecular characterization.
    Microbiol Rev. 1989 Mar;53(1):85-108 PMID: 2651866
  8. Ultrastructural localisation of urease in outer membrane and periplasm of Campylobacter pylori.
    J Clin Pathol. 1989 Jul;42(7):778-9 PMID: 2760239
  9. Two-dimensional gel electrophoresis and immunoblotting of Campylobacter pylori proteins.
    Infect Immun. 1989 Jun;57(6):1825-33 PMID: 2722241
  10. The characterization and pathological significance of gastric Campylobacter-like organisms in the ferret: a model for chronic gastritis?
    Epidemiol Infect. 1988 Oct;101(2):269-78 PMID: 3181311
  11. Cytopathic effects of Campylobacter pylori urease.
    J Clin Pathol. 1988 May;41(5):597 PMID: 3384991
  12. Identification of the outer membrane proteins of Campylobacter pyloridis and antigenic cross-reactivity between C. pyloridis and C. jejuni.
    J Gen Microbiol. 1987 Jan;133(1):163-70 PMID: 3309141
  13. Campylobacter-like organisms isolated from gastric mucosa of ferrets.
    Am J Vet Res. 1986 Feb;47(2):236-9 PMID: 3954197
  14. Helicobacter pylori acid resistance.
    Lancet. 1990 May 19;335(8699):1232 PMID: 1971083
  15. Hypothesis: Helicobacter pylori, urease, mucus, and gastric ulcer.
    Lancet. 1990 Jan 27;335(8683):193-5 PMID: 1967668
  16. Purification and characterization of urease from Helicobacter pylori.
    J Biol Chem. 1990 Jun 5;265(16):9464-9 PMID: 2188975
  17. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation.
    J Infect Dis. 1990 Apr;161(4):626-33 PMID: 2181029
  18. Campylobacter pylori: its link to gastritis and peptic ulcer disease.
    Rev Infect Dis. 1990 Jan-Feb;12 Suppl 1:S87-93 PMID: 2406862
  19. Urea protects Helicobacter (Campylobacter) pylori from the bactericidal effect of acid.
    Gastroenterology. 1990 Sep;99(3):697-702 PMID: 2379775
  20. Helicobacter mustelae-associated gastritis in ferrets. An animal model of Helicobacter pylori gastritis in humans.
    Gastroenterology. 1990 Aug;99(2):352-61 PMID: 2365188
  21. Helicobacter pylori urease activity is toxic to human gastric epithelial cells.
    Infect Immun. 1990 Jun;58(6):1992-4 PMID: 2341188
  22. Nucleotide sequence of two genes from Helicobacter pylori encoding for urease subunits.
    Nucleic Acids Res. 1990 Jan 25;18(2):362 PMID: 2326167
  23. Comparison of isolates of Helicobacter pylori and Helicobacter mustelae.
    J Clin Microbiol. 1991 Feb;29(2):395-7 PMID: 2007648
Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
Published
1991-09-00
Pages
3343-5
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC258181
Subset
IM
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