Kinetic studies on immune hemolysis; a method.

The Journal of experimental medicine ·Vol. 88 ·No. 4 ·1948-10-01 ·Pages 427-44

MAYER MM, CROFT CC, GRAY MM

Abstract

A quantitative method for the study of the kinetics of immune hemolysis is described. In the presence of excess C' and limited amounts of antibody the kinetics of hemolysis resemble those of enzymatic processes. Assays of hemolytic antibody should therefore be based on velocity measurements rather than end point titrations.

Keywords

HEMOLYSIS

MeSH Terms

Antibodies Hemolysis Humans Kinetics

Chemicals

Antibodies

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

MAYER M M

CROFT C C

GRAY M M

References (2)

2 references, click to expand

THE ACTIVATING EFFECT OF MAGNESIUM AND OTHER CATIONS ON THE HEMOLYTIC FUNCTION OF COMPLEMENT.
J Exp Med. 1946 Nov 30;84(6):535-48 PMID: 19871586
QUANTITATIVE CHEMICAL STUDIES ON COMPLEMENT OR ALEXIN : II. THE INTERRELATION OF COMPLEMENT WITH ANTIGEN-ANTIBODY COMPOUNDS AND WITH SENSITIZED RED CELLS.
J Exp Med. 1941 May 31;73(6):695-709 PMID: 19871106

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.88.4.427

Published

1948-10-01

Pages

427-44

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2135836

Subset

External Links

PubMed source DOI: 10.1084/jem.88.4.427 PMC Full Text View journal details

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