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PMID: 18892426 Published · ppublish English Journal Article

The relation of infectious and hemagglutination titers to the adaptation of influenza virus to mice.

The Journal of experimental medicine ·Vol. 88 ·No. 5 ·1948-11-00 ·Pages 515-9

WANG CI

Abstract

The non-pathogenic (unadapted) line of the Rhodes strain of influenza virus multiplied readily in the mouse lung, but its rate of multiplication was slower and its hemagglutination titer attained at the peak of growth was much lower than that of the adapted line of the same virus. The implication of these findings to mouse adaptability of the virus is discussed.

Keywords
INFLUENZA A/experimental
MeSH Terms
Adaptation, Physiological Animals Hemagglutination Humans Influenza A virus Influenza, Human Mice Orthomyxoviridae
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
WANG C I
References (2)
2 references, click to expand
  1. THE AGGLUTINATION OF RED CELLS BY ALLANTOIC FLUID OF CHICK EMBRYOS INFECTED WITH INFLUENZA VIRUS.
    Science. 1941 Jul 4;94(2427):22-3 PMID: 17777315
  2. STUDIES ON THE MECHANISM OF ADAPTATION OF INFLUENZA VIRUS TO MICE.
    J Exp Med. 1947 Oct 31;86(5):357-66 PMID: 19871683
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1948-11-00
Pages
515-9
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2135838
Subset
OM
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