Structure and function of herpesvirus saimira DNA.

IARC scientific publications ·No. 11 Pt 1 ·1975-00-00 ·Pages 145-9

Fleckenstein B, Bornkamm GW

Abstract

Two types of genomes are present in HVS stocks: (1) the defective H-genome consisting of highly reiterated heavy (71% C+G) sequences; and (2) the M-genome, which carries the whole genetic information of HVS and is infectious in tissue culture. The sequences in the M-genome are made up of 70% unique L-DNA (with 36% C + G) and 30% H-DNA, which is highly repetitive. H-sequences in the M-genome are clustered at the ends of the molecule.

MeSH Terms

Animals Base Sequence Callitrichinae Cell Transformation, Neoplastic DNA, Viral/physiology Genes Haplorhini Helper Viruses Herpesviridae/physiology Herpesvirus 2, Saimiriine/physiology Lymphoma/etiology Molecular Weight Mutation Neoplasms, Experimental/etiology Nucleic Acid Renaturation Simplexvirus

Chemicals

DNA, Viral

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Fleckenstein B

Bornkamm G W

Article Info

Journal

IARC scientific publications

Abbr.

IARC Sci Publ

Published

1975-00-00

Pages

145-9

Language

English

Region

France

NLM ID

0364347

Subset

External Links

PubMed source

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Structure and function of herpesvirus saimira DNA.

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