Collagenase is a component of the specific granules of human neutrophil leucocytes.

The Biochemical journal ·Vol. 162 ·No. 1 ·1977-01-15 ·Pages 195-7

Murphy G, Reynolds JJ, Bretz U, Baggiolini M

Abstract

Azurophil and specific granules were isolated from human polymorphonuclear neutrophil leucocytes. Collagenase was almost exclusively a component of the specific granules. This finding is in contrast with the distribution of other proteolytic enzymes, which are localized in the azurophil (or lysosomal) granules.

MeSH Terms

Electrophoresis, Polyacrylamide Gel Humans Microbial Collagenase/metabolism Neutrophils/enzymology,ultrastructure

Chemicals

Microbial Collagenase

Authors & Affiliations

4 authors, click to expand affiliations / ORCID

Murphy G

Reynolds J J

Bretz U

Baggiolini M

References (21)

21 references, click to expand

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Article Info

Journal

The Biochemical journal

Abbr.

Biochem J

ISSN

0264-6021

DOI

10.1042/bj1620195

Published

1977-01-15

Pages

195-7

Language

English

Region

England

NLM ID

2984726R

PMCID

PMC1164583

Subset

External Links

PubMed source DOI: 10.1042/bj1620195 PMC Full Text View journal details

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Collagenase is a component of the specific granules of human neutrophil leucocytes.

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