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PMID: 19245616 Published · ppublish English Journal Article

Clinical evaluation of Alfaxan-CD(R) as an intravenous anaesthetic in young cats.

Australian veterinary journal ·Vol. 87 ·No. 3 ·2009-03-00 ·页码 82-7

Zaki S, Ticehurst K, Miyaki Y

Abstract

To describe and evaluate the use of Alfaxan-CD as an intravenous anaesthetic in young cats. Thirty-five Domestic Short-hair cats aged from 3 to 12 months were admitted into the University Veterinary Teaching Hospital-Sydney for elective surgery. Anaesthesia was induced with Alfaxan-CD and maintained with isoflurane: 22 cats received no premedication and 13 cats received acepromazine (0.03 mg/kg) and butorphanol (0.3 mg/kg) subcutaneously 30 min prior to induction. Qualitative and quantitative data for induction and recovery were recorded. Physiological parameters were recorded at 0, 2 and 5 min post induction, and every 5 min thereafter until the end of the procedure. Intravenous injection of Alfaxan-CD resulted in rapid induction of anaesthesia with a mean time to intubation of 122 s. The mean dose of Alfaxan-CD used was 4.2 mg/kg in unpremedicated cats and 2.7 mg/kg in premedicated cats. All cats maintained a heart rate above 95 beats/min. No cat developed hypoxaemia. Hypercapnoea was detected in 4 cats and hypotension was observed in 18 cats. Time to extubation ranged from 1 to 9 min. The mean time to sternal recumbency for premedicated cats was 11 min; 77% of premedicated cats and 23% of unpremedicated cats had a recovery score of 1 or 2. Alfaxan-CD is an effective anaesthetic agent in young healthy cats, providing a smooth induction and rapid recovery. Cats that were premedicated with acepromazine and butorphanol prior to induction with Alfaxan-CD had better recovery scores than those that were not premedicated.

MeSH 主题词
Acepromazine/administration & dosage Anesthesia Recovery Period Anesthesia, Intravenous/methods,veterinary Anesthetics, Intravenous/administration & dosage Animals Animals, Newborn/physiology Blood Pressure/drug effects Butorphanol/administration & dosage Cats/physiology Female Heart Rate/drug effects Isoflurane/administration & dosage Male Oxygen Consumption Pregnanediones/administration & dosage Premedication/veterinary Random Allocation Respiration/drug effects Time Factors
化学物质
Anesthetics, Intravenous Pregnanediones Acepromazine alphaxalone Isoflurane Butorphanol
作者与单位
共 3 位作者,点击展开单位 / ORCID
Zaki S
Anaesthesia Unit, University Veterinary Teaching Hospital-Sydney, The University of Sydney, New South Wales 2006, Australia. [email protected]
Ticehurst Ke
Miyaki Y
Article Info
Journal
Australian veterinary journal
Abbr.
Aust Vet J
ISSN
0005-0423
Corresponding email
Published
2009-03-00
页码
82-7
Language
English
Country/Region
England
NLM ID
0370616
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