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PMID: 19431878 Published · ppublish English Journal Article

Modification of supported lipid membranes by atomic force microscopy.

Biophysical journal ·Vol. 64 ·No. 3 ·1993-03-00 ·Pages 898-902

Brandow SL, Turner DC, Ratna BR, Gaber BP

Abstract

The atomic force microscope (AFM) was used to structurally modify supported lipid bilayers in a controlled quantitative manner. By increasing the force applied by the AFM tip, lipid was removed from the scanned area, leaving a cut through the lipid bilayer. Cuts were repaired with the AFM by scanning the region with a controlled force and driving lipid back into the cut. A slow self-annealing of cuts was also observed.

Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Brandow S L
Center for Biomolecular Science and Engineering, Naval Research Laboratory, Washington, DC 20375-5000 USA.
Turner D C
Ratna B R
Gaber B P
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Article Info
Journal
Biophysical journal
Abbr.
Biophys J
ISSN
0006-3495
DOI
10.1016/S0006-3495(93)81450-4
Published
1993-03-00
Pages
898-902
Language
English
Region
United States
NLM ID
0370626
PMCID
PMC1262403
External Links
PubMed source DOI: 10.1016/S0006-3495(93)81450-4 PMC Full Text View journal details
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