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PMID: 19592286 Published · ppublish English Journal Article

Intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine.

Journal of feline medicine and surgery ·Vol. 11 ·No. 8 ·2009-08-00 ·Pages 668-82

Roomp K, Rand J

Abstract

Human diabetic patients routinely self-adjust their insulin dose using a protocol and home monitoring, and perform equally well or outperform physician directed adjustments. The objective of this study was to report the outcome of home monitoring of diabetic cats by owners using a protocol aimed at achieving euglycaemia, using ultra-low carbohydrate diets (< or =10% metabolisable energy) and the insulin analogue glargine for >10 weeks and/or until remission was achieved. Fifty-five cats diagnosed with diabetes mellitus, whose owners joined the online German Diabetes-Katzen Forum, were included. An overall remission rate of 64% was achieved in the cohort. Significantly higher remission rates were observed if good glycaemic control was achieved soon after diagnosis: 84% for cats started on the protocol within 6 months of diagnosis went into remission, and only 35% for cats that began more than 6 months after diagnosis (P<0.001). Only one mild clinical hypoglycaemic episode occurred observed despite tight blood glucose control. In conclusion, intensive blood glucose control is safe and effective in diabetic cats using home monitoring and treatment with glargine.

MeSH Terms
Animals Blood Glucose/analysis Blood Glucose Self-Monitoring/methods,veterinary Cat Diseases/blood,epidemiology,therapy Cats Comorbidity Diabetes Mellitus, Type 1/blood,epidemiology,therapy,veterinary Diabetes Mellitus, Type 2/blood,epidemiology,therapy,veterinary Dietary Carbohydrates/administration & dosage Female Germany/epidemiology Hypoglycemic Agents/administration & dosage Insulin/administration & dosage,analogs & derivatives Insulin Glargine Insulin, Long-Acting Male Treatment Outcome
Chemicals
Blood Glucose Dietary Carbohydrates Hypoglycemic Agents Insulin Insulin, Long-Acting Insulin Glargine
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Roomp Kirsten
Department of Computational Biology and Applied Algorithmics, Max Planck Institute for Informatics, Saarbrücken, Germany.
Rand Jacquie
Article Info
Journal
Journal of feline medicine and surgery
Abbr.
J Feline Med Surg
ISSN
1098-612X
Published
2009-08-00
Epub
2009-00-09
Pages
668-82
Language
English
Region
England
NLM ID
100897329
Subset
IM
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