Home LiteratureArticle Details
PMID: 19609734 Published · ppublish ger English Abstract Journal Article Review

[Wound healing after endoscopic sinus surgery and postoperative management].

Wundheilung und postoperative Behandlung nach Nasennebenhöhlenoperationen.

HNO ·Vol. 57 ·No. 8 ·2009-08-00 ·Pages 763-71

Beule AG, Hosemann W

Abstract

Understanding the physiological concepts of wound healing after rhinologic procedures facilitates detection and management of more or less obvious problems of wound healing. In this review, the physiologic processes involved in wound healing are explained, and typical clinical constellations are presented. Based on challenges of anatomy and physiology, recent findings are summarized, and possible conclusions for managing the postoperative mucosa are drawn.

MeSH Terms
Endoscopy/methods Humans Nose Diseases/surgery Otorhinolaryngologic Surgical Procedures/methods Paranasal Sinuses/surgery Postoperative Care/methods
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Beule A G
Klinik und Poliklinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Halschirurgie der Universität Greifswald, Walther-Rathenau-Strasse 43-45, 17475, Greifswald. [email protected]
Hosemann W
References (56)
56 references, click to expand
  1. Does nasal irrigation enter paranasal sinuses in chronic rhinosinusitis?
    Am J Rhinol. 2008 Sep-Oct;22(5):483-6 PMID: 18954507
  2. Composition of hyaluronan affects wound healing in the rabbit maxillary sinus.
    Am J Rhinol. 2006 Mar-Apr;20(2):206-11 PMID: 16686391
  3. Use of hylan B gel as a wound dressing after endoscopic sinus surgery.
    J Otolaryngol. 2002 Aug;31 Suppl 1:S41-4 PMID: 12243243
  4. Relationship between the frequency of postoperative debridement and patient discomfort, healing period, surgical outcomes, and compliance after endoscopic sinus surgery.
    Laryngoscope. 2008 Oct;118(10):1868-72 PMID: 18641526
  5. Normal wound healing of the paranasal sinuses: clinical and experimental investigations.
    Eur Arch Otorhinolaryngol. 1991;248(7):390-4 PMID: 1747245
  6. [Nuclear medicine studies of the regenerative behavior of paranasal sinus mucosa after functional endoscopic ethmoid bone surgery].
    HNO. 1991 May;39(5):173-6 PMID: 1874633
  7. Mucosal healing and mucociliary transport change after endoscopic sinus surgery in children with chronic maxillary sinusitis.
    Int J Pediatr Otorhinolaryngol. 2006 Aug;70(8):1361-7 PMID: 16519952
  8. [Experimental studies of wound healing in the paranasal sinuses. II. Spontaneous wound healing and drug effects in a standardized wound model].
    HNO. 1991 Feb;39(2):48-54 PMID: 2032874
  9. The effects of retinoic acid on ciliary function of regenerated sinus mucosa.
    Am J Rhinol. 2008 May-Jun;22(3):334-6 PMID: 18588770
  10. Effect of nerve growth factor and keratinocyte growth factor on wound healing of the sinus mucosa.
    Wound Repair Regen. 2008 Jan-Feb;16(1):108-16 PMID: 18086292
  11. Regeneration of maxillary sinus mucosa following surgical removal. Experimental study in rabbits.
    Ann Otol Rhinol Laryngol. 1993 Jun;102(6):459-66 PMID: 8512274
  12. Long-term effects of postoperative measures after sinus surgery.
    Eur Arch Otorhinolaryngol. 2008 May;265(5):531-7 PMID: 17960410
  13. Pre- and postoperative sinus penetration of nasal irrigation.
    Laryngoscope. 2008 Nov;118(11):2078-81 PMID: 18641522
  14. Comparison of delivery of topical medications to the paranasal sinuses via "vertex-to-floor" position and atomizer spray after FESS.
    Otolaryngol Head Neck Surg. 2005 Nov;133(5):735-40 PMID: 16274802
  15. Effects of fibrin sealant-containing antibiotics in a rabbit model of chronic sinusitis.
    Am J Rhinol. 2000 Jul-Aug;14(4):233-40 PMID: 10979496
  16. Effects of a novel chitosan gel on mucosal wound healing following endoscopic sinus surgery in a sheep model of chronic rhinosinusitis.
    Laryngoscope. 2008 Jun;118(6):1088-94 PMID: 18401274
  17. Postoperative care following endoscopic sinus surgery.
    Rhinology. 2004 Sep;42(3):114-20 PMID: 15521662
  18. Comparison of conventional instruments and mechanical debriders for surgery of patients with chronic sinusitis.
    Am J Rhinol. 2003 Jul-Aug;17(4):197-202 PMID: 12962188
  19. Anatomical changes of the ethmoid cavity after endoscopic sinus surgery.
    Laryngoscope. 2008 Dec;118(12):2240-4 PMID: 19029868
  20. Topical steroid drops for the treatment of sinus ostia stenosis in the postoperative period.
    Am J Rhinol. 2006 Nov-Dec;20(6):563-7 PMID: 17181093
  21. MeroGel hyaluronic acid sinonasal implants: osteogenic implications.
    Laryngoscope. 2002 Jan;112(1):37-42 PMID: 11802036
  22. Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9).
    Crit Rev Biochem Mol Biol. 2002 Dec;37(6):375-536 PMID: 12540195
  23. Cutaneous wound healing.
    N Engl J Med. 1999 Sep 2;341(10):738-46 PMID: 10471461
  24. Effects of a dexamethasone-releasing stent on osteoneogenesis in a rabbit model.
    Am J Rhinol Allergy. 2009 Jul-Aug;23(4):433-6 PMID: 19671262
  25. A prospective controlled trial of pulsed nasal nebulizer in maximally dissected cadavers.
    Am J Rhinol. 2008 Jul-Aug;22(4):390-4 PMID: 18702903
  26. Effects of topically applied dexamethasone on mucosal wound healing using a drug-releasing stent.
    Laryngoscope. 2008 Nov;118(11):2073-7 PMID: 18849860
  27. Efficacy of different techniques of sinonasal irrigation after modified Lothrop procedure.
    Am J Rhinol Allergy. 2009 Jan-Feb;23(1):85-90 PMID: 19379619
  28. Influence of the application of platelet-enriched plasma in oral mucosal wound healing.
    Clin Oral Implants Res. 2007 Feb;18(1):133-9 PMID: 17224034
  29. Impact of perioperative systemic steroids on surgical outcomes in patients with chronic rhinosinusitis with polyposis: evaluation with the novel Perioperative Sinus Endoscopy (POSE) scoring system.
    Laryngoscope. 2007 Nov;117(11 Pt 2 Suppl 115):1-28 PMID: 18075447
  30. Impact of chronic rhinosinusitis and endoscopic sinus surgery on bone remodeling of the paranasal sinuses.
    Am J Rhinol. 2008 Sep-Oct;22(5):537-41 PMID: 18954517
  31. Effect of topical mitomycin C for antrostomy in rabbit with sinusitis.
    Eur Arch Otorhinolaryngol. 2006 Oct;263(10):917-23 PMID: 16786365
  32. Impact of pulsatile nasal irrigation on the prognosis of functional endoscopic sinus surgery.
    J Otolaryngol Head Neck Surg. 2008 Apr;37(2):148-53 PMID: 19128603
  33. Mucosal wound healing after nasal surgery. A controlled clinical trial on the efficacy of hyaluronic acid containing cream.
    Drugs Exp Clin Res. 1999;25(6):253-61 PMID: 10713863
  34. Hemostatic agent microporous polysaccharide hemospheres (MPH) does not affect healing or intact sinus mucosa.
    Laryngoscope. 2008 Jul;118(7):1265-9 PMID: 18438268
  35. Initial report on postoperative healing after endoscopic sinus surgery with the microdebrider.
    Otolaryngol Head Neck Surg. 1998 Jun;118(6):800-3 PMID: 9627240
  36. Cutting forceps in functional endoscopic sinus surgery.
    Acta Otorhinolaryngol Belg. 2000;54(1):29-37 PMID: 10719591
  37. Treatment alternatives for chronic rhinosinusitis persisting after ESS: what to do when antibiotics, steroids and surgery fail.
    Rhinology. 2008 Mar;46(1):3-14 PMID: 18444486
  38. Frontal ostium restenosis after the endoscopic modified Lothrop procedure.
    Laryngoscope. 2007 Aug;117(8):1457-62 PMID: 17585278
  39. Matrix metalloproteinases MMP-7, MMP-9 and their tissue inhibitor TIMP-1: expression in chronic sinusitis vs nasal polyposis.
    Allergy. 2004 Jan;59(1):54-60 PMID: 14674934
  40. Matrix metalloproteinase 9 level predicts optimal collagen deposition during early wound repair in humans.
    Br J Surg. 1998 Jan;85(1):68-71 PMID: 9462387
  41. [Effects of postoperative care on wound healing after endonasal paranasal sinus surgery].
    Laryngorhinootologie. 1996 Apr;75(4):208-14 PMID: 8688126
  42. Regeneration of nerve fibres in the maxillary sinus mucosa after experimental surgery. An immunocytochemical double-labelling study in the rabbit.
    Acta Otolaryngol. 1999;119(4):486-91 PMID: 10445066
  43. The effects of sulfurous-arsenical-ferruginous thermal water nasal irrigation in wound healing after functional endoscopic sinus surgery for chronic rhinosinusitis: a prospective randomized study.
    Am J Otolaryngol. 2008 Jul-Aug;29(4):223-9 PMID: 18598831
  44. [Review: pathophysiology and methodology of nasal packing].
    Laryngorhinootologie. 2004 Aug;83(8):534-51; quiz 553-6 PMID: 15316896
  45. Frontal ostium neo-osteogenesis and restenosis after modified endoscopic Lothrop procedure in an animal model.
    Clin Otolaryngol Allied Sci. 2004 Aug;29(4):386-8 PMID: 15270828
  46. The effect of endoscopic sinus surgery on mucociliary activity and healing of maxillary sinus mucosa.
    Rhinology. 2000 Sep;38(3):120-3 PMID: 11072657
  47. Predictive and monitoring value of matrix metalloproteinase-9 for healing quality after sinus surgery.
    Wound Repair Regen. 2004 Jul-Aug;12(4):412-8 PMID: 15260806
  48. [Experimental studies of wound healing in the paranasal sinuses. III. Endoscopy and histology of the surgical area after endonasal ethmoidectomy].
    HNO. 1991 Mar;39(3):111-5 PMID: 2050553
  49. Wound healing for the dermatologic surgeon.
    J Dermatol Surg Oncol. 1988 Sep;14(9):959-72 PMID: 3045181
  50. Secretion of TGF-betal, TGF-beta2, EGF and PDGF into nasal fluid after sinus surgery.
    Eur Arch Otorhinolaryngol. 2002 May;259(5):234-8 PMID: 12107524
  51. The effect of a dissolvable hyaluronic acid-based pack on the healing of the nasal mucosa of sheep.
    Am J Rhinol. 2002 Mar-Apr;16(2):85-90 PMID: 12030362
  52. Winter's concept of moist wound healing: a review of the evidence and impact on clinical practice.
    J Wound Care. 2005 Jun;14(6):273-6 PMID: 15974414
  53. Wound healing of the nasal and paranasal mucosa: a review.
    Am J Rhinol. 2002 Mar-Apr;16(2):77-84 PMID: 12030361
  54. The effect of insulin-like growth factor 1 incorporated into a hyaluronic acid-based nasal pack on nasal mucosal healing in a healthy sheep model and a sheep model of chronic sinusitis.
    Am J Rhinol. 2005 May-Jun;19(3):251-6 PMID: 16011130
  55. Platelet gel for endoscopic sinus surgery.
    Ann Otol Rhinol Laryngol. 2005 Sep;114(9):699-704 PMID: 16240933
  56. Comparing the microdebrider and standard instruments in endoscopic sinus surgery: a double-blind randomised study.
    B-ENT. 2007;3(1):1-7 PMID: 17451119
Article Info
Journal
HNO
Abbr.
HNO
ISSN
1433-0458
DOI
10.1007/s00106-009-1938-8
Email
[email protected]
Published
2009-08-00
Pages
763-71
Language
ger
Region
Germany
NLM ID
2985099R
Subset
IM
External Links
PubMed source DOI: 10.1007/s00106-009-1938-8 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: [email protected]

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2