Pluripotent stem cells and disease modeling.

Cell stem cell ·Vol. 5 ·No. 3 ·2009-09-04 ·Pages 244-7

Colman A, Dreesen O

Abstract

Human embryonic stem cells (hESCs) and induced pluripotent stem cells (hiPSCs) can theoretically be converted into any somatic cell type. hESCs and hiPSCs carrying genetic defects can now be produced to model diseases in vitro. We suggest several guiding principles to help ensure an optimal fit between technology and disease.

MeSH Terms

Animals Disease Disease Models, Animal Embryonic Stem Cells/cytology Humans Models, Biological Pluripotent Stem Cells/cytology

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Colman Alan

Institute of Medical Biology, Singapore, Singapore. [email protected]

Dreesen Oliver

Article Info

Journal

Cell stem cell

Abbr.

Cell Stem Cell

ISSN

1875-9777

DOI

10.1016/j.stem.2009.08.010

[email protected]

Published

2009-09-04

Pages

244-7

Language

English

Region

United States

NLM ID

101311472

Subset

External Links

PubMed source DOI: 10.1016/j.stem.2009.08.010 View journal details

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