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PMID: 1980996 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

The human Y chromosome shows a low level of DNA polymorphism.

Annals of human genetics ·Vol. 54 ·No. 4 ·1990-00-00 ·Pages 297-305

Malaspina P, Persichetti F, Novelletto A, Iodice C, Terrenato L, Wolfe J, Ferraro M, Prantera G

Abstract

Six new Y-specific probes have been isolated and are reported. Along with another six already described they have been used in a systemic search for male specific RFLPs. An overall number of 46515 nucleotides have been screened with 12 enzymes and no polymorphic pattern observed. Our data reveal a greatly reduced level of polymorphism compared with other chromosomes.

MeSH Terms

Animals Chromosome Banding DNA Probes Female Humans Hybrid Cells Male Mice Polymorphism, Restriction Fragment Length Restriction Mapping Y Chromosome

Chemicals

DNA Probes

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Malaspina P

Dipartimento di Biologia, Università Tor Vergata, Rome, Italy.

Persichetti F

Novelletto A

Iodice C

Terrenato L

Wolfe J

Ferraro M

Prantera G

Article Info

Journal

Annals of human genetics

Abbr.

Ann Hum Genet

ISSN

0003-4800

DOI

10.1111/j.1469-1809.1990.tb00385.x

Published

1990-00-00

Pages

297-305

Language

English

Region

England

NLM ID

0416661

Subset

External Links

PubMed source DOI: 10.1111/j.1469-1809.1990.tb00385.x View journal details

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The human Y chromosome shows a low level of DNA polymorphism.

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