STUDIES ON THE EFFECT OF CERTAIN MACROMOLECULAR SUBSTANCES ON THE RESPIRATORY ACTIVITY OF THE LEUCOCYTES OF PERIPHERAL BLOOD.

The Journal of experimental medicine ·Vol. 112 ·No. 4 ·1960-09-30 ·Pages 653-69

Strauss BS, Stetson CA

Abstract

The oxygen, uptake of lightly heparinized human blood was found to increase markedly upon the addition of bacterial endotoxins, soluble antigen-antibody complexes, or polystyrene latex particles. The effect apparently reflects a transitory stimulation of respiratory activity of the blood leucocytes. The effect did not occur in the presence of anticoagulant amounts of citrate or ethylenediaminetetraacetate, was inhibited by iodoacetate and fluoride ions, and may be related to the energy-yielding processes involved in histamine release or phagocytosis.

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Strauss B S

Department of Pathology, New York University School of Medicine, New York.

Stetson C A

References (14)

14 references, click to expand

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Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.112.4.653

Published

1960-09-30

Pages

653-69

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2137241

External Links

PubMed source DOI: 10.1084/jem.112.4.653 PMC Full Text View journal details

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STUDIES ON THE EFFECT OF CERTAIN MACROMOLECULAR SUBSTANCES ON THE RESPIRATORY ACTIVITY OF THE LEUCOCYTES OF PERIPHERAL BLOOD.

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