THE MULTIPLICATION OF FIBROBLASTS IN VITRO.
1. It may be concluded that, under the conditions of the experiments and within the limits of accuracy of the method, the temporary multiplication of fibroblasts cultivated in the plasma of an adult animal is not due to the serum. It may be attributed to the presence of a small amount of embryonic juice within the tissue itself. 2. The indefinite multiplication of fibroblasts in a medium composed of adult plasma and of embryonic juice is due neither to the serum nor to the fibrin. It depends entirely on substances contained in the embryonic juice. 3. There is a definite relation between the rate of growth and the concentration of the embryonic juice in the medium.
7 references, click to expand
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A STRAIN OF CONNECTIVE TISSUE SEVEN YEARS OLD.J Exp Med. 1919 Nov 30;30(6):531-7 PMID: 19868375
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ON THE PERMANENT LIFE OF TISSUES OUTSIDE OF THE ORGANISM.J Exp Med. 1912 May 1;15(5):516-28 PMID: 19867545
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MEASUREMENT OF THE GROWTH OF TISSUES IN VITRO.J Exp Med. 1921 Aug 31;34(3):231-43 PMID: 19868554
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THE PERMANENT LIFE OF CONNECTIVE TISSUE OUTSIDE OF THE ORGANISM.J Exp Med. 1913 Mar 1;17(3):273-85 PMID: 19867643
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FIBRIN AND SERUM AS A CULTURE MEDIUM.J Exp Med. 1921 Apr 30;33(5):641-6 PMID: 19868523
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CONTRIBUTIONS TO THE STUDY OF THE MECHANISM OF THE GROWTH OF CONNECTIVE TISSUE.J Exp Med. 1913 Sep 1;18(3):287-98 PMID: 19867704
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STUDIES UPON THE CHARACTERISTICS OF DIFFERENT CULTURE MEDIA AND THEIR INFLUENCE UPON THE GROWTH OF TISSUE OUTSIDE OF THE ORGANISM.J Exp Med. 1912 Oct 1;16(4):421-31 PMID: 19867583
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