STUDIES ON THE OXIDATION-REDUCTION OF HEMOGLOBIN AND METHEMOGLOBIN : III. THE FORMATION OF METHEMOGLOBIN DURING THE OXIDATION OF AUTOXIDIZABLE SUBSTANCES.

The Journal of experimental medicine ·Vol. 41 ·No. 4 ·1925-03-31 ·Pages 551-60

Neill JM

Abstract

Hemoglobin is oxidized to methemoglobin by products formed during the oxidation of a number of different substances. With some of these substances, both oxygen consumption and hemoglobin oxidation are accelerated by thermolabile constituents of pneumococci; with others of the easily oxidized substances, neither reaction seems to be influenced by the presence of the bacterial substances. The same substances which in the presence of air induce the oxidation of hemoglobin bring about the reverse reaction if molecular oxygen is excluded.

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Neill J M

Hospital of The Rockefeller Institute for Medical Research.

References (7)

7 references, click to expand

Mechanism of Oxidation in the Plant: Part I. The Oxygenase of Bach and Chodat: Function of Lecithins in Respiration.
Biochem J. 1923;17(4-5):515-29 PMID: 16743245
STUDIES ON THE OXIDATION-REDUCTION OF HEMOGLOBIN AND METHEMOGLOBIN : II. THE OXIDATION OF HEMOGLOBIN AND REDUCTION OF METHEMOGLOBIN BY ANAEROBIC BACILLI AND BY STERILE PLANT TISSUE.
J Exp Med. 1925 Mar 31;41(4):535-49 PMID: 19869007
STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : V. THE DESTRUCTION OF OXYHEMOGLOBIN BY STERILE EXTRACTS OF PNEUMOCOCCUS.
J Exp Med. 1924 Apr 30;39(5):757-75 PMID: 19868882
STUDIES ON PNEUMOCOCCUS GROWTH INHIBITION : II. A METHOD FOR DEMONSTRATING THE GROWTH-INHIBITORY AND BACTERICIDAL ACTION OF NORMAL SERUM-LEUCOCYTE MIXTURES.
J Exp Med. 1924 Jan 31;39(2):219-44 PMID: 19868840
STUDIES ON THE OXIDATION-REDUCTION OF HEMOGLOBIN AND METHEMOGLOBIN : I. THE CHANGES INDUCED BY PNEUMOCOCCI AND BY STERILE ANIMAL TISSUE.
J Exp Med. 1925 Jan 31;41(2):299-313 PMID: 19868989
STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : II. THE PRODUCTION OF PEROXIDE BY STERILE EXTRACTS OF PNEUMOCOCCUS.
J Exp Med. 1924 Feb 29;39(3):357-66 PMID: 19868851
STUDIES ON OXIDATION AND REDUCTION BY PNEUMOCOCCUS : VIII. NATURE OF THE OXIDATION-REDUCTION SYSTEMS IN STERILE PNEUMOCOCCUS EXTRACTS.
J Exp Med. 1925 Jan 31;41(2):285-98 PMID: 19868988

Article Info

Journal

The Journal of experimental medicine

Abbr.

J Exp Med

ISSN

0022-1007

DOI

10.1084/jem.41.4.551

Published

1925-03-31

Pages

551-60

Language

English

Region

United States

NLM ID

2985109R

PMCID

PMC2130961

External Links

PubMed source DOI: 10.1084/jem.41.4.551 PMC Full Text View journal details

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STUDIES ON THE OXIDATION-REDUCTION OF HEMOGLOBIN AND METHEMOGLOBIN : III. THE FORMATION OF METHEMOGLOBIN DURING THE OXIDATION OF AUTOXIDIZABLE SUBSTANCES.

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