PHYSIOLOGICAL ONTOGENY : A. CHICKEN EMBRYOS. IV. THE NEGATIVE ACCELERATION OF GROWTH WITH AGE AS DEMONSTRATED BY TISSUE CULTURES.
1. Observations on tissue cultures of heart muscle from chicken embryos indicate that in general the growth rate of the individual cells decreases with age. The negative acceleration of growth is greatest at the beginning of life as in the intact embryo. 2. The latent period before growth commences increases with the age of the implanted tissue, but in a different fashion. The acceleration of the latent period is greatest near the end of the incubation period, thus demonstrating that the factors determining the initiation of growth and those determining the extent of growth are not similar.
6 references, click to expand
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AGE AND MULTIPLICATION OF FIBROBLASTS.J Exp Med. 1921 Nov 30;34(6):599-623 PMID: 19868581
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STUDIES ON THE METABOLISM OF CELLS IN VITRO : I. THE TOXICITY OFalpha-AMINO-ACIDS FOR EMBRYONIC CHICKEN CELLS.J Exp Med. 1917 Jan 1;25(1):93-108 PMID: 19868081
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ACTION OF SERUM ON FIBROBLASTS IN VITRO.J Exp Med. 1923 May 31;37(6):759-65 PMID: 19868757
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THE LATENT PERIOD IN THE GROWTH OF BACTERIA.J Exp Med. 1916 Oct 1;24(4):387-418 PMID: 19868050
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STUDIES ON BACTERIAL NUTRITION : IV. EFFECT OF PLANT TISSUE UPON GROWTH OF PNEUMOCOCCUS AND STREPTOCOCCUS.J Exp Med. 1923 Jul 31;38(2):207-17 PMID: 19868784
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MEASUREMENT OF THE GROWTH OF TISSUES IN VITRO.J Exp Med. 1921 Aug 31;34(3):231-43 PMID: 19868554
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