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PMID: 19869077 Published · ppublish English Journal Article

THE EFFECT OF ETHYL URETHANE ANESTHESIA ON THE ACID-BASE EQUILIBRIUM AND CELL CONTENTS OF THE BLOOD.

The Journal of experimental medicine ·Vol. 42 ·No. 5 ·1925-10-31 ·Pages 609-18

Hawkins JA, Murphy JB

Abstract

When anesthesia is produced in rabbits or rats by injections of ethyl urethane, the C0(2) content and pH of the whole blood of the animal are more or less rapidly increased to a point where there is a marked uncompensated alkalosis which reaches its maximum at 24 hours and persists for 48 hours. The increase in the C0(2) content and pH of the whole blood is accompanied by a decrease in the circulating lymphocytes and an increase in the polymorphonuclear leucocytes.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Hawkins J A
Laboratories of The Rockefeller Institute for Medical Research.
Murphy J B
References (1)
1 references, click to expand
  1. An Apparatus for Determination of the Gases in Blood and Other Solutions.
    Proc Natl Acad Sci U S A. 1921 Aug;7(8):229-31 PMID: 16576595
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1925-10-31
Pages
609-18
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2131063
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