STUDIES ON IMMUNOLOGICAL RELATIONSHIPS AMONG THE PNEUMOCOCCI : II. A COMPARISON OF THE ANTIBODY RESPONSES OF MICE AND OF RABBITS TO IMMUNIZATION WITH TYPICAL TYPE III PNEUMOCOCCI AND TO IMMUNIZATION WITH A RELATED STRAIN.
The paper reports an experimental comparison of the antibody responses of mice and of rabbits to immunization with typical Type III pneumococci and a strain related to Type III. The results as a whole show that the relative antigenic effectiveness of these two kinds of related pneumococci, is different in different animals. In rabbits the strain related to but not identical with Type III elicits the better response; in mice, the typical Type III strain is more effective. These relationships furnish an example of the influence of the species of animal upon the effectiveness of even closely related bacterial antigens.
4 references, click to expand
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A NOTE ON THE PRODUCTION OF ANTIPNEUMOCOCCUS SERA.J Exp Med. 1917 May 1;25(5):629-32 PMID: 19868113
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STUDIES ON IMMUNITY TO PNEUMOCOCCUS MUCOSUS (TYPE III) : I. ANTIBODY RESPONSE OF RABBITS IMMUNIZED WITH TYPE III PNEUMOCOCCUS.J Exp Med. 1927 Mar 31;45(4):713-26 PMID: 19869284
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STUDIES ON IMMUNITY TO PNEUMOCOCCUS MUCOSUS (TYPE III) : II. THE INFECTIVITY OF TYPE III PNEUMOCOCCUS FOR RABBITS.J Exp Med. 1927 May 31;45(6):1093-106 PMID: 19869308
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STUDIES ON IMMUNOLOGICAL RELATIONSHIPS AMONG THE PNEUMOCOCCI : I. A VIRULENT STRAIN OF PNEUMOCOCCUS WHICH Is IMMUNOLOGICALLY RELATED TO, BUT NOT IDENTICAL WITH TYPICAL STRAINS OF TYPE III PNEUMOCOCCI.J Exp Med. 1928 May 31;47(6):917-31 PMID: 19869454
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