A STUDY OF VACCINAL IMMUNITY IN TISSUE CULTURES.
Normal corneas inoculated in vitro with vaccine virus and then cultivated in antivaccinal plasma developed typical vaccinal lesions associated with Guarnieri bodies. In such cultures, after an incubation period of 24 or 48 hours, active vaccine virus was demonstrated by means of appropriate methods. Immune corneas inoculated in vitro with vaccine virus and then cultivated in normal or in antivaccinal plasma revealed either very mild vaccinal lesions or none at all. In some of the cultures after 24 and 48 hours of incubation, active vaccine virus was demonstrated.
7 references, click to expand
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Studies on Filterable Viruses: III. Further Observations on Vaccine Virus.Am J Pathol. 1929 Mar;5(2):147-55 PMID: 19969838
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ISOLATION BY CATAPHORESIS OF VIRUS FROM VACCINIA-RECOVERED RABBITS.Science. 1929 Feb 8;69(1780):170 PMID: 17806489
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GROWTH AND PERSISTENCE OF FILTERABLE VIRUSES IN A TRANSPLANTABLE RABBIT NEOPLASM.J Exp Med. 1925 Sep 30;42(4):523-37 PMID: 19869072
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A FILTERABLE VIRUS PRESENT IN THE SUBMAXILLARY GLANDS OF GUINEA PIGS.J Exp Med. 1926 Nov 30;44(6):855-73 PMID: 19869228
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A STUDY OF CANCER IMMUNITY BY THE METHOD OF CULTIVATING TISSUES OUTSIDE THE BODY.J Exp Med. 1911 May 1;13(5):505-10 PMID: 19867431
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DEVELOPMENT IN TISSUE CULTURES OF THE INTRACELLULAR CHANGES CHARACTERISTIC OF VACCINAL AND HERPETIC INFECTIONS.J Exp Med. 1929 Oct 31;50(5):665-72 PMID: 19869653
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THE PRODUCTION OF ANTIBODIES BY TISSUES LIVING OUTSIDE OF THE ORGANISM.J Exp Med. 1912 Mar 1;15(3):287-91 PMID: 19867523
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