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PMID: 19869778 Published · ppublish English Journal Article

IMMUNITY TO POLIOMYELITIS IN MOTHERS AND THE NEWBORN AS SHOWN BY THE NEUTRALIZATION TEST.

The Journal of experimental medicine ·Vol. 52 ·No. 4 ·1930-09-30 ·Pages 457-64

Aycock WL, Kramer SD

Abstract

Neutralization tests for the virus of poliomyelitis on blood serum of urban mothers and their newborn infants showed that immunity was present in ten out of twelve (83 per cent) infants and in ten out of twelve (83 per cent) mothers, with a complete correspondence between mother and infant. These tests point to passive transmission of immunity from mother to infant. Previous tests on other children (1 to 5 years) indicate that immunity in infants is transitory. Previous observations concerning the extent of immunity in urban adults are confirmed and extended. The results of these tests are in accord with the age distribution of poliomyelitis and parallel corresponding observations in diphtheria.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Aycock W L
Department of Preventive Medicine and Hygiene, Harvard Medical School, Boston, and the Research Laboratory of the Vermont Department of Public Health, Burlington.
Kramer S D
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1930-09-30
Pages
457-64
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2131894
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