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PMID: 19869935 Published · ppublish English Journal Article

THE EFFECT OF TESTICLE EXTRACT AND OF NORMAL SERUM ON A TRANSPLANTABLE EPITHELIAL TUMOR OF THE RABBIT.

The Journal of experimental medicine ·Vol. 54 ·No. 4 ·1931-09-30 ·Pages 493-8

Duran-Reynals F

Abstract

Extract of rat, rabbit or bull testicle prevents or retards the growth of a rabbit tumor when a mixture of the extract and a tumor cell suspension is inoculated intradermally. Similar mixtures, made with normal rabbit serum instead of testicle extract, give rise to tumors which grow with unusual rapidity. The results are the opposite of those obtained with pathogenic bacteria or filtrable viruses which are enhanced by testicle extract and generally inhibited by normal serum.

Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Duran-Reynals F
Laboratories of The Rockefeller Institute for Medical Research.
References (5)
5 references, click to expand
  1. THE EFFECT OF TESTICLE EXTRACT ON RED BLOOD CELLS IN VITRO.
    J Exp Med. 1931 Jul 31;54(2):197-206 PMID: 19869910
  2. PROPERTIES OF THE CAUSATIVE AGENT OF A CHICKEN TUMOR : I. THE SPECIFIC FIXATION BY TISSUES OF SUSCEPTIBLE ANIMALS.
    J Exp Med. 1929 Aug 31;50(3):315-26 PMID: 19869625
  3. THE EFFECT OF EXTRACTS OF CERTAIN ORGANS FROM NORMAL AND IMMUNIZED ANIMALS ON THE INFECTING POWER OF VACCINE VIRUS.
    J Exp Med. 1929 Aug 31;50(3):327-40 PMID: 19869626
  4. THE EFFECT OF SECONDARY INFECTIONS ON EXPERIMENTAL TRACHOMA.
    J Exp Med. 1931 Apr 30;53(5):753-62 PMID: 19869878
  5. THE INFLUENCE OF TESTICLE EXTRACT ON THE INTRADERMAL SPREAD OF INJECTED FLUIDS AND PARTICLES.
    J Exp Med. 1931 Feb 28;53(3):387-98 PMID: 19869851
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1931-09-30
Pages
493-8
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2132018
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