THE ACTION OF A SPECIFIC ENZYME UPON THE DERMAL INFECTION OF RABBITS WITH TYPE III PNEUMOCOCCUS.
The action of the enzyme which specifically decomposes the capsular polysaccharide of Type III Pneumococcus has been tested in Type III pneumococcus dermal infections in rabbits. When injected in sufficient amounts, this enzyme is capable of bringing about a favorable and early termination of the experimental disease which ordinarily is fatal in nearly all instances. The results of the present study yield further evidence that the capsular substance is of great importance in pneumococcus infection, since, in so far as known, the only action of which the specific enzyme is capable is that of decomposing the capsular polysaccharide.
8 references, click to expand
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EXPERIMENTAL INTRADERMAL PNEUMOCOCCUS INFECTION IN RABBITS.J Exp Med. 1928 Jun 30;48(1):1-20 PMID: 19869464
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FACTORS AFFECTING THE YIELD OF SPECIFIC ENZYME IN CULTURES OF THE BACILLUS DECOMPOSING THE CAPSULAR POLYSACCHARIDE OF TYPE III PNEUMOCOCCUS.J Exp Med. 1932 Feb 29;55(3):377-91 PMID: 19869997
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THE DEVELOPMENT AND LOCALIZATION OF THE DERMAL PNEUMOCOCCIC LESION IN THE RABBIT.J Exp Med. 1931 Nov 30;54(6):847-58 PMID: 19869964
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THE PATHOLOGY OF EXPERIMENTAL DERMAL PNEUMOCOCCUS INFECTION IN THE RABBIT.J Exp Med. 1931 Jun 30;54(1):41-50 PMID: 19869901
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FURTHER EXPERIMENTS WITH THE INTRADERMAL PNEUMOCOCCUS INFECTION IN RABBITS.J Exp Med. 1928 Aug 31;48(3):413-29 PMID: 19869495
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THE PRODUCTION OF INFECTION WITH PNEUMOCOCCI IN RABBITS BY INTRADERMAL INOCULATION OF TYPE III PNEUMOCOCCI, THE TREATMENT WITH SPECIFIC ANTISERUM, AND A COMPARISON WITH TYPE I INFECTIONS.J Exp Med. 1930 Nov 30;52(6):849-63 PMID: 19869808
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STUDIES ON IMMUNITY TO PNEUMOCOCCUS MUCOSUS (TYPE III) : II. THE INFECTIVITY OF TYPE III PNEUMOCOCCUS FOR RABBITS.J Exp Med. 1927 May 31;45(6):1093-106 PMID: 19869308
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THE SPECIFIC ACTION OF A BACTERIAL ENZYME ON PNEUMOCOCCI OF TYPE III.Science. 1930 Aug 8;72(1858):151-2 PMID: 17838541
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