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PMID: 19870013 Published · ppublish English Journal Article

STUDIES ON THE CULTIVATION OF THE TYPHUS FEVER RICKETTSIA IN THE PRESENCE OF LIVE TISSUE.

The Journal of experimental medicine ·Vol. 55 ·No. 4 ·1932-03-31 ·Pages 563-76

Nigg C, Landsteiner K

Abstract

1. Rickettsia prowazeki can be cultivated for many generations in vitro, without diminution in numbers or virulence, in media similar to those described by Maitland, Rivers, and others for the cultivation of certain viruses. In all probability, such cultures can be maintained indefinitely. 2. It has been impossible, thus far, to cultivate the typhus rickettsia without employing living tissue.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Nigg C
Laboratories of The Rockefeller Institute for Medical Research.
Landsteiner K
References (8)
8 references, click to expand
  1. OBSERVATIONS CONCERNING THE PERSISTENCE OF LIVING CELLS IN MAITLAND'S MEDIUM FOR THE CULTIVATION OF VACCINE VIRUS.
    J Exp Med. 1929 Jul 31;50(2):181-7 PMID: 19869613
  2. TYPHUS FEVER : I. COMPARATIVE STUDY OF EUROPEAN AND AMERICAN TYPHUS IN LABORATORY ANIMALS.
    J Exp Med. 1931 Jul 31;54(2):181-6 PMID: 19869908
  3. DEVELOPMENT IN TISSUE CULTURES OF THE INTRACELLULAR CHANGES CHARACTERISTIC OF VACCINAL AND HERPETIC INFECTIONS.
    J Exp Med. 1929 Oct 31;50(5):665-72 PMID: 19869653
  4. The Cultivation of the Micro-Organisms of Rocky Mountain spotted Fever (Dermacentroxenus Rickettsi) and of Typhus (Rickettsia Prowazeki) in Tissue Cultures.
    J Med Res. 1923 Dec;44(2):231-256.1 PMID: 19972597
  5. STUDIES ON MEXICAN TYPHUS FEVER. I.
    J Exp Med. 1930 May 31;51(6):847-58 PMID: 19869731
  6. THE GROWTH AND DEATH OF TISSUE CULTURES EXPOSED TO SUPRANORMAL TEMPERATURES.
    J Exp Med. 1931 Jul 31;54(3):323-32 PMID: 19869920
  7. TYPHUS FEVER : III. THE BEHAVIOR OF RICKETTSIA PROWAZEKI IN TISSUE CULTURES.
    J Exp Med. 1931 Jul 31;54(3):307-14 PMID: 19869918
  8. CULTIVATION OF VACCINE VIRUS.
    J Exp Med. 1930 Sep 30;52(4):465-70 PMID: 19869779
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1932-03-31
Pages
563-76
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2132120
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