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PMID: 19870181 Published · ppublish English Journal Article

THE ANTIGENIC RELATIONSHIP BETWEEN PROTEUS X-19 AND TYPHUS RICKETTSIAE : A STUDY OF THE WEIL-FELIX REACTION.

The Journal of experimental medicine ·Vol. 58 ·No. 1 ·1933-06-30 ·Pages 55-62

Castaneda MR, Zia S

Abstract

1. The absorption of typhus sera (human or antityphus horse serum) with Proteus X-19 removes only the Proteus agglutinins, leaving the Rickettsia agglutinins intact. 2. The absorption of typhus sera with Mexican Rickettsiae removes the agglutinins for both the Rickettsia and Proteus X-19. 3. While normal or formalinized Rickettsiae are not agglutinated by anti-Proteus serum, these organisms-when formalinized and heated at 75 degrees C.-become agglutinable by such serum. 4. The absorption of anti-Proteus serum with Mexican Rickettsiae removes agglutinins for formalinized and heated Rickettsiae but does not affect those for Proteus X-19.

Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Castaneda M R
Department of Bacteriology and Immunology of the Harvard University Medical School, Boston.
Zia S
References (2)
2 references, click to expand
  1. STUDIES ON THE ANTIGENIC SUBSTANCE OF THE BACTERIAL CELL.
    J Exp Med. 1925 Aug 31;42(3):311-21 PMID: 19869054
  2. STUDIES ON TYPHUS FEVER : IX. ON THE SERUM REACTIONS OF MEXICAN AND EUROPEAN TYPHUS RICKETTSIA.
    J Exp Med. 1932 Sep 30;56(4):455-67 PMID: 19870078
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1933-06-30
Pages
55-62
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2132277
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