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PMID: 19870412 Published · ppublish English Journal Article

ISOLATION OF POLIOMYELITIS VIRUS FROM THE NASOPHARYNX.

The Journal of experimental medicine ·Vol. 62 ·No. 2 ·1935-07-31 ·Pages 245-57

Paul JR, Trask JD, Webster LT

Abstract

A single example of mild illness diagnosed as suspected abortive poliomyelitis is described in which the virus of poliomyelitis was recovered from the nasopharynx by three different methods. Failure to recover virus from a total of twenty-six cases diagnosed as suspected or abortive poliomyelitis and fourteen contacts is also reported. The original material from the nasopharynx of the positive case proved unusually infective for the monkey, apparently even more so than are the majority of suspensions of spinal cords from fatal human cases of poliomyelitis. An explanation of this fact is not clear. The method of isolating human virus from the throat, by means of preserving the sediment of washings from this site in glycerine, has been shown to be efficient in one case for a period of 101 days.

Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Paul J R
Departments of Medicine and Pediatrics, Yale University School of Medicine, New Haven, and the Laboratories of The Rockefeller Institute for Medical Research, New York.
Trask J D
Webster L T
References (3)
3 references, click to expand
  1. Use of Serum and the Routine and Experimental Laboratory Findings in the 1934 Poliomyelitis Epidemic.
    Am J Public Health Nations Health. 1934 Dec;24(12):1215-23 PMID: 18014093
  2. CARRIAGE OF THE VIRUS OF POLIOMYELITIS, WITH SUBSEQUENT DEVELOPMENT OF THE INFECTION.
    J Exp Med. 1917 Nov 1;26(5):745-54 PMID: 19868179
  3. THE DETECTION OF POLIOMYELITIS VIRUS IN SO CALLED ABORTIVE TYPES OF THE DISEASE.
    J Exp Med. 1932 Aug 31;56(3):319-43 PMID: 19870068
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1935-07-31
Pages
245-57
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2133270
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