CHEMICAL STUDIES ON BACTERIAL AGGLUTINATION : II. THE IDENTITY OF PRECIPITIN AND AGGLUTININ.
1. The absolute, quantitative agglutinin method has been used for the determination of the presence or absence of small amounts of specific polysaccharide in pneumococcus variants. 2. A technique is described for the removal of group specific antibody from antipneumococcus horse serum. 3. The type specific anticarbohydrate agglutinin and precipitin are not only present in identical amounts in Type I antipneumococcus horse serum, but a reduction in one is also accompanied by a quantitatively identical reduction in the other, providing evidence for their actual identity. In purified antibody solutions somewhat more agglutinin than precipitin is found, possibly owing to alteration of a portion of the antibody in the process of purification.
10 references, click to expand
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SPECIFIC PRECIPITATION AND MOUSE PROTECTION IN TYPE I ANTIPNEUMOCOCCUS SERA.J Exp Med. 1930 Sep 30;52(4):477-83 PMID: 19869781
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THE PRECIPITIN REACTION BETWEEN TYPE III PNEUMOCOCCUS POLYSACCHARIDE AND HOMOLOGOUS ANTIBODY : II. CONDITIONS FOR QUANTITATIVE PRECIPITATION OF ANTIBODY IN HORSE SERA.J Exp Med. 1935 Mar 31;61(4):559-62 PMID: 19870379
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CHEMICAL STUDIES ON BACTERIAL AGGLUTINATION : I. A METHOD.J Exp Med. 1934 Oct 31;60(5):643-53 PMID: 19870328
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CHEMOIMMUNOLOGICAL STUDIES ON THE SOLUBLE SPECIFIC SUBSTANCE OF PNEUMOCOCCUS : I. THE ISOLATION AND PROPERTIES OF THE ACETYL POLYSACCHARIDE OF PNEUMOCOCCUS TYPE I.J Exp Med. 1933 Nov 30;58(6):731-55 PMID: 19870226
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AGGLUTINATION BY PRECIPITIN.J Exp Med. 1927 Jul 31;46(2):303-14 PMID: 19869340
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SPECIFIC AND NON-SPECIFIC POLYSACCHARIDES OF TYPE IV PNEUMOCOCCUS.J Exp Med. 1931 Apr 30;53(5):625-39 PMID: 19869869
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THE TRANSFORMATION OF PNEUMOCOCCAL TYPES : I. THE CONVERSION OF R FORMS OF PNEUMOCOCCUS INTO S FORMS OF THE HOMOLOGOUS TYPE.J Exp Med. 1930 Jan 1;51(1):99-122 PMID: 19869681
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QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : ANTIBODY PRODUCTION IN RABBITS INJECTED WITH AN AZO PROTEIN.J Exp Med. 1933 Jul 31;58(2):137-52 PMID: 19870185
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THE INTERCONVERTIBILITY OF "R" AND "S" FORMS OF PNEUMOCOCCUS.J Exp Med. 1928 Mar 31;47(4):577-91 PMID: 19869432
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QUANTITATIVE STUDIES ON THE PRECIPITIN REACTION : THE DETERMINATION OF SMALL AMOUNTS OF A SPECIFIC POLYSACCHARIDE.J Exp Med. 1932 Mar 31;55(4):555-61 PMID: 19870012
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