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PMID: 19870519 Published · ppublish English Journal Article

EFFECT OF PURIFIED ENZYMES ON VIRUSES AND GRAM-NEGATIVE BACTERIA.

The Journal of experimental medicine ·Vol. 64 ·No. 1 ·1936-06-30 ·Pages 19-28

Merrill MH

Abstract

Evidence is presented that some viruses behave like proteins in that they are inactivated by proteolytic enzymes, whereas others prove more or less resistant. Ten strains of living Gram-negative bacteria resisted the action of purified trypsin and chymotrypsin, while the killed organisms were rapidly digested. Gram-positive bacteria, on the other hand, were resistant whether living or dead. The findings are discussed.

Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Merrill M H
Department of Animal and Plant Pathology of The Rockefeller Institute for Medical Research, Princeton, N. J.
References (3)
3 references, click to expand
  1. Differentiation between Gram-positive and Gram-negative Microörganisms by the use of Enzymes.
    J Bacteriol. 1933 Oct;26(4):361-71 PMID: 16559662
  2. ISOLATION OF A CRYSTALLINE PROTEIN POSSESSING THE PROPERTIES OF TOBACCO-MOSAIC VIRUS.
    Science. 1935 Jun 28;81(2113):644-5 PMID: 17743301
  3. ISOLATION OF A CRYSTALLINE PROTEIN FROM PANCREAS AND ITS CONVERSION INTO A NEW CRYSTALLINE PROTEOLYTIC ENZYME BY TRYPSIN.
    Science. 1933 Dec 15;78(2033):558-9 PMID: 17811936
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1936-06-30
Pages
19-28
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2133419
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