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PMID: 19870996 Published · ppublish English Journal Article

I. POLIOMYELITIC VIRUS IN HUMAN STOOLS.

The Journal of experimental medicine ·Vol. 71 ·No. 6 ·1940-05-31 ·Pages 751-63

Trask JD, Paul JR, Vignec AJ

Abstract

1. The detection of the virus of poliomyelitis in 10 stools from 8 individuals is reported. All were in relation to epidemic poliomyelitis and 7 of them represented well recognized forms of the disease. The positive stools were distributed among 56 specimens collected from 53 persons in the first 4 weeks of illness. 2. The ease of detection of virus was directly related to the non-paralytic type of disease and inversely related to the age of the patients. 3. The negative results with stools employed for controls gives point to the use of the fecal examinations as an epidemiological tool. 4. The stability of the virus in feces has been demonstrated by successful mailing of samples over long distances and during the heat of summer. 5. At least one infective dose per gram of fecal material was extracted from one stool.

Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Trask J D
Departments of Pediatrics and Medicine of the Yale University School of Medicine, and the Pediatric and the Medical Services of the New Haven Hospital and Dispensary, New Haven.
Paul J R
Vignec A J
References (3)
3 references, click to expand
  1. POLIOMYELITIC VIRUS IN SEWAGE.
    Science. 1939 Sep 15;90(2333):258-9 PMID: 17737857
  2. A CUTANEOUS TEST FOR TUBERCULOSIS IN PRIMATES.
    Science. 1939 May 12;89(2315):442-3 PMID: 17816952
  3. II. POLIOMYELITIC VIRUS IN URBAN SEWAGE.
    J Exp Med. 1940 May 31;71(6):765-77 PMID: 19870997
Article Info
Journal
The Journal of experimental medicine
Abbr.
J Exp Med
ISSN
0022-1007
Published
1940-05-31
Pages
751-63
Language
English
Region
United States
NLM ID
2985109R
PMCID
PMC2135104
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